| Title |
Effects of multiple training modalities in patients with Alzheimer’s disease: a pilot study
|
|---|---|
| Published in |
Neuropsychiatric Disease and Treatment, November 2016
|
| DOI | 10.2147/ndt.s116257 |
| Pubmed ID | |
| Authors |
Shu-Yu Tai, Chia-Ling Hsu, Shu-Wan Huang, Tzu-Chiao Ma, Wen-Chien Hsieh, Yuan-Han Yang |
| Abstract |
This pilot study investigated the effects of multiple training modalities on cognition, neuropsychiatric symptoms, caregivers' burden, and quality of life in patients with Alzheimer's disease (AD). This intervention study was conducted in 24 patients with AD aged ≥65 years with a Clinical Dementia Rating (CDR) score of 0.5-1. The patients were assigned to receive multiple training modalities (1 hour for each training: Tai Chi, calligraphy, and drawing) over a 6-week period in either the experimental group (n=14) or the comparison group (n=10). A series of neuropsychological tests - namely the Traditional Chinese version Mini-Mental Status Examination, Cognitive Assessment Screening Instrument (CASI), Neuropsychiatric Inventory and the Neuropsychiatric Inventory Caregiver Distress Scale, and the Clinical Dementia Rating Sum of Boxes scale - were conducted at the baseline and after the intervention. The World Health Organization Quality of Life-BREF (WHOQOL-BREF) and Zarit Caregiver Burden Scale were used to assess the quality of life and caregivers' burden, respectively. Independent sample t-test and paired sample t-test were used to analyze the data. After the intervention, the experimental group reported higher scores in the orientation domain of CASI (P=0.007) and in the psychiatry domain of WHOQOL-BREF (P=0.042) compared with the comparison group. Caregivers' distress was significantly decreased in the experimental group (P=0.035) but not in the comparison group (P=0.430). The multiple training modalities improved scores in the orientation domain of CASI and psychiatry domain of WHOQOL-BREF in patients with AD. Moreover, the intervention reduced caregivers' distress. |
Mendeley readers
The data shown below were compiled from readership statistics for 104 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 104 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 18 | 17% |
| Student > Bachelor | 14 | 13% |
| Researcher | 12 | 12% |
| Student > Doctoral Student | 10 | 10% |
| Student > Ph. D. Student | 9 | 9% |
| Other | 14 | 13% |
| Unknown | 27 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 25 | 24% |
| Nursing and Health Professions | 21 | 20% |
| Medicine and Dentistry | 9 | 9% |
| Neuroscience | 7 | 7% |
| Social Sciences | 6 | 6% |
| Other | 9 | 9% |
| Unknown | 27 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 November 2016.
All research outputs
#4,760,513
of 25,374,917 outputs
Outputs from Neuropsychiatric Disease and Treatment
#643
of 3,132 outputs
Outputs of similar age
#72,266
of 317,812 outputs
Outputs of similar age from Neuropsychiatric Disease and Treatment
#20
of 77 outputs
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We're also able to compare this research output to 77 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.