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Preparation of an antitumor and antivirus agent: chemical modification of α-MMC and MAP30 from Momordica Charantia L. with covalent conjugation of polyethyelene glycol

Overview of attention for article published in International Journal of Nanomedicine, June 2012
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1 video uploader

Citations

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39 Dimensions

Readers on

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41 Mendeley
Title
Preparation of an antitumor and antivirus agent: chemical modification of α-MMC and MAP30 from Momordica Charantia L. with covalent conjugation of polyethyelene glycol
Published in
International Journal of Nanomedicine, June 2012
DOI 10.2147/ijn.s30631
Pubmed ID
Authors

Xiaojun Zhao, Meng, Li, Liu, Meng

Abstract

Alpha-momorcharin (α-MMC) and momordica anti-HIV protein (MAP30) derived from Momordica charantia L. have been confirmed to possess antitumor and antivirus activities due to their RNA-N-glycosidase activity. However, strong immunogenicity and short plasma half-life limit their clinical application. To solve this problem, the two proteins were modified with (mPEG)(2)-Lys-NHS (20 kDa).

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 41 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 12 29%
Student > Bachelor 8 20%
Professor > Associate Professor 4 10%
Student > Ph. D. Student 4 10%
Other 2 5%
Other 6 15%
Unknown 5 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 20%
Biochemistry, Genetics and Molecular Biology 8 20%
Medicine and Dentistry 6 15%
Chemistry 4 10%
Pharmacology, Toxicology and Pharmaceutical Science 3 7%
Other 4 10%
Unknown 8 20%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 March 2013.
All research outputs
#11,056,833
of 12,438,331 outputs
Outputs from International Journal of Nanomedicine
#2,166
of 2,456 outputs
Outputs of similar age
#120,782
of 144,509 outputs
Outputs of similar age from International Journal of Nanomedicine
#32
of 51 outputs
Altmetric has tracked 12,438,331 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,456 research outputs from this source. They receive a mean Attention Score of 3.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 144,509 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 51 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.