| Title |
Alveolar epithelial and endothelial cell apoptosis in emphysema: What we know and what we need to know
|
|---|---|
| Published in |
International Journal of Chronic Obstructive Pulmonary Disease, December 2008
|
| DOI | 10.2147/copd.s4432 |
| Pubmed ID | |
| Authors |
Mathieu C Morissette, Julie Parent, Julie Milot |
| Abstract |
Emphysema is mainly caused by cigarette smoking and is characterized by the loss of alveolar integrity and an enlargement of the alveolar space. However, mechanisms involved in its development are not fully understood. Alveolar cell apoptosis has been previously investigated in the lung of emphysematous subjects as a potential contributor to the loss of alveolar cell and has been found abnormally elevated. Though, mechanisms involved in the increased alveolar apoptosis that occurs in emphysema have now become a prolific field of research. Those mechanisms are reviewed here with special focus on how they affect cell viability and how they may be implicated in emphysema. Moreover, we suggest a model that integrates all those mechanisms to explain the increased alveolar apoptosis observed in emphysema. This review also includes some reflections and suggestions on the research to come. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 4 | 6% |
| United States | 1 | 2% |
| Canada | 1 | 2% |
| Brazil | 1 | 2% |
| Unknown | 56 | 89% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 12 | 19% |
| Student > Ph. D. Student | 11 | 17% |
| Researcher | 10 | 16% |
| Student > Doctoral Student | 7 | 11% |
| Student > Bachelor | 5 | 8% |
| Other | 9 | 14% |
| Unknown | 9 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 18 | 29% |
| Agricultural and Biological Sciences | 15 | 24% |
| Biochemistry, Genetics and Molecular Biology | 10 | 16% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 6% |
| Nursing and Health Professions | 2 | 3% |
| Other | 3 | 5% |
| Unknown | 11 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 September 2023.
All research outputs
#20,657,128
of 25,374,917 outputs
Outputs from International Journal of Chronic Obstructive Pulmonary Disease
#2,078
of 2,577 outputs
Outputs of similar age
#168,106
of 179,603 outputs
Outputs of similar age from International Journal of Chronic Obstructive Pulmonary Disease
#15
of 17 outputs
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We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.