Title |
Skin rejuvenation using cosmetic products containing growth factors, cytokines, and matrikines: a review of the literature
|
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Published in |
Clinical, Cosmetic and Investigational Dermatology, November 2016
|
DOI | 10.2147/ccid.s116158 |
Pubmed ID | |
Authors |
Caroline Aldag, Diana Nogueira Teixeira, Phillip S Leventhal |
Abstract |
Skin aging is primarily due to alterations in the dermal extracellular matrix, especially a decrease in collagen I content, fragmentation of collagen fibrils, and accumulation of amorphous elastin material, also known as elastosis. Growth factors and cytokines are included in several cosmetic products intended for skin rejuvenation because of their ability to promote collagen synthesis. Matrikines and matrikine-like peptides offer the advantage of growth factor-like activities but better skin penetration due to their much smaller molecular size. In this review, we summarize the commercially available products containing growth factors, cytokines, and matrikines for which there is evidence that they promote skin rejuvenation. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 29% |
Unknown | 5 | 71% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 7 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Iran, Islamic Republic of | 1 | <1% |
Italy | 1 | <1% |
Unknown | 250 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 39 | 15% |
Researcher | 38 | 15% |
Student > Bachelor | 38 | 15% |
Student > Ph. D. Student | 18 | 7% |
Student > Postgraduate | 16 | 6% |
Other | 33 | 13% |
Unknown | 70 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 42 | 17% |
Medicine and Dentistry | 41 | 16% |
Pharmacology, Toxicology and Pharmaceutical Science | 29 | 12% |
Agricultural and Biological Sciences | 24 | 10% |
Chemistry | 14 | 6% |
Other | 28 | 11% |
Unknown | 74 | 29% |