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Considerations in selecting rapid-onset opioids for the management of breakthrough pain

Overview of attention for article published in Journal of Pain Research, March 2013
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Mentioned by

twitter
1 tweeter

Citations

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27 Dimensions

Readers on

mendeley
34 Mendeley
Title
Considerations in selecting rapid-onset opioids for the management of breakthrough pain
Published in
Journal of Pain Research, March 2013
DOI 10.2147/jpr.s40745
Pubmed ID
Authors

Howard Smith

Abstract

Breakthrough pain (BTP) is a transitory pain that occurs despite the use of long-term, around-the-clock analgesia. It is highly prevalent in certain populations and places a significant burden on patients, their families, caregivers, and health-care systems. Despite its prevalence and impact, BTP is sometimes unrecognized and often undertreated. Various formulations of fentanyl - a rapid-onset opioid with short duration of action - are available for the management of BTP. The efficacy of formulations using transmucosal, transbuccal, sublingual, and intranasal administration routes has been demonstrated for BTP treatment in clinical trials. However, a lack of head-to-head trials evaluating their relative efficacy makes it challenging for physicians to reach informed decisions on the most efficacious intervention for individual patients. In the absence of clear data on the relative efficacy of fentanyl formulations, prescribing decisions need to be based on physician understanding and experience and product cost and availability, taking into account the individual patient's needs, the ability of the patient or caregivers to administer medication, and the patient's wishes. This review evaluates current pharmacologic methods of alleviating BTP and discusses factors that should be considered when selecting the most appropriate formulation for individual patients. With the range of fentanyl formulations available, it is now possible to successfully address BTP in the majority of patients.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 34 100%

Demographic breakdown

Readers by professional status Count As %
Other 6 18%
Student > Ph. D. Student 5 15%
Researcher 4 12%
Student > Master 4 12%
Student > Postgraduate 3 9%
Other 9 26%
Unknown 3 9%
Readers by discipline Count As %
Medicine and Dentistry 15 44%
Pharmacology, Toxicology and Pharmaceutical Science 4 12%
Agricultural and Biological Sciences 4 12%
Biochemistry, Genetics and Molecular Biology 2 6%
Business, Management and Accounting 1 3%
Other 3 9%
Unknown 5 15%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 March 2013.
All research outputs
#5,295,303
of 6,230,503 outputs
Outputs from Journal of Pain Research
#288
of 334 outputs
Outputs of similar age
#79,908
of 98,431 outputs
Outputs of similar age from Journal of Pain Research
#19
of 22 outputs
Altmetric has tracked 6,230,503 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 334 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 98,431 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.