Title |
Psychosurgery for schizophrenia: history and perspectives
|
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Published in |
Neuropsychiatric Disease and Treatment, April 2013
|
DOI | 10.2147/ndt.s35823 |
Pubmed ID | |
Authors |
Matheus Schmidt Soares, Wellingson Silva Paiva, Eda Z Guertzenstein, Robson Luis Amorim, Luca Silveira Bernardo, Jose Francisco Pereira, Erich Talamoni Fonoff, Manoel Jacobsen Teixeira |
Abstract |
Following the early studies of Moniz and Lima, psychosurgery had considerable scientific credibility until the advent of modern antipsychotics in the mid 1950s. Thereafter, psychosurgery was almost abandoned in large medical centers as a common treatment for schizophrenia, although is still used for some affective and anxiety disorders. We reviewed relevant papers cited in the Medline/Index Medicus, Cochrane, and Scielo databases from 1930 to 2012. In our review of the literature, we show from recent studies that there are still many patients with schizophrenia who have serious deficits even after being treated with current noninvasive therapies. The value of psychosurgery remains controversial. There are no data available to support the use of stereotactic procedures for schizophrenia. Well designed controlled trials are needed to establish the effectiveness of psychosurgery in patients with schizophrenia. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 14% |
Unknown | 6 | 86% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 5 | 71% |
Scientists | 2 | 29% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | 1% |
Brazil | 1 | 1% |
Unknown | 76 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 18 | 23% |
Researcher | 11 | 14% |
Student > Ph. D. Student | 6 | 8% |
Student > Master | 6 | 8% |
Student > Postgraduate | 5 | 6% |
Other | 13 | 17% |
Unknown | 19 | 24% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 21 | 27% |
Psychology | 16 | 21% |
Agricultural and Biological Sciences | 5 | 6% |
Neuroscience | 4 | 5% |
Biochemistry, Genetics and Molecular Biology | 3 | 4% |
Other | 9 | 12% |
Unknown | 20 | 26% |