| Title |
Effect of famotidine on the pharmacokinetics of apixaban, an oral direct factor Xa inhibitor
|
|---|---|
| Published in |
Clinical Pharmacology : Advances and Applications, April 2013
|
| DOI | 10.2147/cpaa.s41999 |
| Pubmed ID | |
| Authors |
Vijay V Upreti, Yan Song, Jessie Wang, Wonkyung Byon, Rebecca A Boyd, Janice M Pursley, Frank LaCreta, Charles E Frost |
| Abstract |
Apixaban is an oral, selective, direct factor Xa inhibitor approved for thromboprophylaxis after orthopedic surgery and stroke prevention in patients with atrial fibrillation, and under development for treatment of venous thromboembolism. This study investigated the effect of a gastric acid suppressant, famotidine (a histamine H2-receptor antagonist), on the pharmacokinetics of apixaban in healthy subjects. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 76 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Colombia | 1 | 1% |
| France | 1 | 1% |
| Ireland | 1 | 1% |
| United Kingdom | 1 | 1% |
| Slovenia | 1 | 1% |
| Unknown | 71 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 11 | 14% |
| Student > Master | 10 | 13% |
| Other | 7 | 9% |
| Student > Bachelor | 7 | 9% |
| Student > Postgraduate | 7 | 9% |
| Other | 13 | 17% |
| Unknown | 21 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 33 | 43% |
| Pharmacology, Toxicology and Pharmaceutical Science | 8 | 11% |
| Chemistry | 4 | 5% |
| Agricultural and Biological Sciences | 3 | 4% |
| Social Sciences | 1 | 1% |
| Other | 2 | 3% |
| Unknown | 25 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 April 2013.
All research outputs
#20,657,128
of 25,374,917 outputs
Outputs from Clinical Pharmacology : Advances and Applications
#147
of 179 outputs
Outputs of similar age
#163,562
of 212,995 outputs
Outputs of similar age from Clinical Pharmacology : Advances and Applications
#6
of 6 outputs
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So far Altmetric has tracked 179 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one is in the 5th percentile – i.e., 5% of its peers scored the same or lower than it.
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We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one.