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Biomechanical and histological evaluation of the osseointegration capacity of two types of zirconia implant

Overview of attention for article published in International Journal of Nanomedicine, December 2016
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Title
Biomechanical and histological evaluation of the osseointegration capacity of two types of zirconia implant
Published in
International Journal of Nanomedicine, December 2016
DOI 10.2147/ijn.s119519
Pubmed ID
Authors

Jian-min Han, Guang Hong, Hong Lin, Yoshinaka Shimizu, Yuhan Wu, Gang Zheng, Hongyu Zhang, Keiichi Sasaki

Abstract

The purpose of this study was to evaluate the biomechanical and histological behavior of a ceria-stabilized zirconia-alumina nanocomposite (NanoZr) in comparison with that of 3 mol% yttria-stabilized tetragonal zirconia polycrystalline (3Y-TZP) in Sprague Dawley rats. Cylindrical NanoZr and 3Y-TZP implants (diameter 1 mm, length 2 mm) were used. Implant-surface morphology and surface roughness were determined by scanning white-light interferometry and scanning electron microscopy, respectively. The cylindrical zirconia implants were placed at the distal edge of the femur of Sprague Dawley rats. At weeks 2, 4, and 8, the interfacial shear strength between implant and bone was measured by push-in test. Histological analysis was performed using hard-tissue sections. Bone-implant contact (BIC), the thickness of new bone around the implant within the bone marrow area, and osteoclast numbers were evaluated. The average surface roughness of 3Y-TZP (Sa 0.788 μm) was significantly higher than that of NanoZr (Sa 0.559 μm). The shear strengths of 3Y-TZP and NanoZr were similar at 2 weeks, but at 4 and 8 weeks the shear strength of NanoZr was higher than that of 3Y-TZP. The average BIC values within the bone marrow area for 3Y-TZP and NanoZr were 25.26% and 31.51% at 2 weeks, 46.78% and 38% at 4 weeks, and 47.88% and 56.81% at 8 weeks, respectively. The average BIC values within the cortical area were 38.86% and 58.42% at 2 weeks, 66.82% and 57.74% at 4 weeks, and 79.91% and 78.97% at 8 weeks, respectively. The mean BIC value did not differ significantly between the two zirconia materials at any time point. The NanoZr implants were biocompatible, capable of establishing close BIC, and may be preferred for metal-free dental implants.

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Geographical breakdown

Country Count As %
Unknown 85 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 15 18%
Student > Bachelor 15 18%
Student > Postgraduate 7 8%
Student > Ph. D. Student 7 8%
Student > Doctoral Student 5 6%
Other 14 16%
Unknown 22 26%
Readers by discipline Count As %
Medicine and Dentistry 41 48%
Engineering 4 5%
Materials Science 4 5%
Chemical Engineering 3 4%
Unspecified 2 2%
Other 6 7%
Unknown 25 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 December 2016.
All research outputs
#20,823,121
of 25,584,565 outputs
Outputs from International Journal of Nanomedicine
#3,113
of 4,077 outputs
Outputs of similar age
#314,653
of 417,676 outputs
Outputs of similar age from International Journal of Nanomedicine
#58
of 73 outputs
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We're also able to compare this research output to 73 others from the same source and published within six weeks on either side of this one. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.