| Title |
Hypertension and obstructive sleep apnea
|
|---|---|
| Published in |
Nature and science of sleep, May 2013
|
| DOI | 10.2147/nss.s34841 |
| Pubmed ID | |
| Authors |
Craig L Phillips, Denise M O’Driscoll |
| Abstract |
Obstructive sleep apnea (OSA) is increasingly being recognized as a major health burden with strong focus on the associated cardiovascular risk. Studies from the last two decades have provided strong evidence for a causal role of OSA in the development of systemic hypertension. The acute physiological changes that occur during apnea promote nocturnal hypertension and may lead to the development of sustained daytime hypertension via the pathways of sympathetic activation, inflammation, oxidative stress, and endothelial dysfunction. This review will focus on the acute hemodynamic disturbances and associated intermittent hypoxia that characterize OSA and the potential pathophysiological mechanisms responsible for the development of hypertension in OSA. In addition the epidemiology of OSA and hypertension, as well as the role of treatment of OSA, in improving blood pressure control will be examined. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 95 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 1% |
| Australia | 1 | 1% |
| Unknown | 93 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 14 | 15% |
| Student > Master | 12 | 13% |
| Student > Doctoral Student | 11 | 12% |
| Researcher | 9 | 9% |
| Student > Postgraduate | 8 | 8% |
| Other | 15 | 16% |
| Unknown | 26 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 42 | 44% |
| Agricultural and Biological Sciences | 10 | 11% |
| Biochemistry, Genetics and Molecular Biology | 4 | 4% |
| Nursing and Health Professions | 3 | 3% |
| Neuroscience | 3 | 3% |
| Other | 7 | 7% |
| Unknown | 26 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 June 2013.
All research outputs
#20,674,485
of 25,394,764 outputs
Outputs from Nature and science of sleep
#518
of 629 outputs
Outputs of similar age
#155,489
of 204,402 outputs
Outputs of similar age from Nature and science of sleep
#5
of 5 outputs
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