| Title |
Potential and problems in ultrasound-responsive drug delivery systems
|
|---|---|
| Published in |
International Journal of Nanomedicine, April 2013
|
| DOI | 10.2147/ijn.s43589 |
| Pubmed ID | |
| Authors |
Ying-Zheng Zhao, Li-Na Du, Cui-Tao Lu, Yi-Guang Jin, Shu-Ping Ge |
| Abstract |
Ultrasound is an important local stimulus for triggering drug release at the target tissue. Ultrasound-responsive drug delivery systems (URDDS) have become an important research focus in targeted therapy. URDDS include many different formulations, such as microbubbles, nanobubbles, nanodroplets, liposomes, emulsions, and micelles. Drugs that can be loaded into URDDS include small molecules, biomacromolecules, and inorganic substances. Fields of clinical application include anticancer therapy, treatment of ischemic myocardium, induction of an immune response, cartilage tissue engineering, transdermal drug delivery, treatment of Huntington's disease, thrombolysis, and disruption of the blood-brain barrier. This review focuses on recent advances in URDDS, and discusses their formulations, clinical application, and problems, as well as a perspective on their potential use in the future. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 204 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Peru | 2 | <1% |
| Russia | 1 | <1% |
| Unknown | 201 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 41 | 20% |
| Researcher | 29 | 14% |
| Student > Master | 26 | 13% |
| Student > Bachelor | 21 | 10% |
| Student > Postgraduate | 8 | 4% |
| Other | 27 | 13% |
| Unknown | 52 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Engineering | 28 | 14% |
| Medicine and Dentistry | 27 | 13% |
| Chemistry | 24 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 20 | 10% |
| Agricultural and Biological Sciences | 11 | 5% |
| Other | 36 | 18% |
| Unknown | 58 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 November 2023.
All research outputs
#8,039,503
of 25,584,565 outputs
Outputs from International Journal of Nanomedicine
#946
of 4,077 outputs
Outputs of similar age
#65,751
of 213,424 outputs
Outputs of similar age from International Journal of Nanomedicine
#18
of 53 outputs
Altmetric has tracked 25,584,565 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 4,077 research outputs from this source. They receive a mean Attention Score of 4.8. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 213,424 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 53 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.