Title |
Blonanserin treatment in patients with methamphetamine-induced psychosis comorbid with intellectual disabilities
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Published in |
Neuropsychiatric Disease and Treatment, December 2016
|
DOI | 10.2147/ndt.s120374 |
Pubmed ID | |
Authors |
Kosuke Okazaki, Manabu Makinodan, Kazuhiko Yamamuro, Tomoyo Takata, Toshifumi Kishimoto |
Abstract |
Methamphetamine (MA) use has recently been associated with high levels of psychiatric hospitalization and serious social dysfunction. MA use causes frequent psychotic symptoms, which can be treated with antipsychotics. However, people with intellectual disabilities (ID) are vulnerable to adverse effects resulting from treatment with antipsychotic medications. We report two cases of MA-induced psychosis (MAP) in patients with ID who were treated with the antipsychotic blonanserin. In both the cases presented, symptoms of psychosis were improved by switching medications from other antipsychotic drugs to blonanserin. Despite the presence of ID in these patients, no significant adverse effects, such as sedation, were detected after treatment with blonanserin. Blonanserin may be an effective and well-tolerated pharmacotherapeutical treatment for patients with MAP comorbid with ID. However, further work is necessary to validate this claim. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 4% |
Unknown | 22 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 7 | 30% |
Student > Doctoral Student | 3 | 13% |
Other | 1 | 4% |
Student > Bachelor | 1 | 4% |
Librarian | 1 | 4% |
Other | 4 | 17% |
Unknown | 6 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 6 | 26% |
Medicine and Dentistry | 4 | 17% |
Nursing and Health Professions | 2 | 9% |
Social Sciences | 2 | 9% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 4% |
Other | 1 | 4% |
Unknown | 7 | 30% |