| Title |
Magnetic resonance spectroscopy in Alzheimer’s disease
|
|---|---|
| Published in |
Neuropsychiatric Disease and Treatment, May 2013
|
| DOI | 10.2147/ndt.s35440 |
| Pubmed ID | |
| Authors |
Jonathan Graff-Radford, Kejal Kantarci |
| Abstract |
Aging is the primary risk factor for dementia. With increasing life expectancy and aging populations worldwide, dementia is becoming one of the significant public health problems of the century. The most common pathology underlying dementia in older adults is Alzheimer's disease. Proton magnetic resonance spectroscopy (MRS) may provide a window into the biochemical changes associated with the loss of neuronal integrity and other neurodegenerative pathology that involve the brain before the manifestations of cognitive impairment in patients who are at risk for Alzheimer's disease. This review focuses on proton MRS studies in normal aging, mild cognitive impairment, and dementia, and how proton MRS metabolite levels may be potential biomarkers for early diagnosis of dementia-related pathologic changes in the brain. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Turkey | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 141 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | <1% |
| Netherlands | 1 | <1% |
| Austria | 1 | <1% |
| Egypt | 1 | <1% |
| Spain | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 135 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 34 | 24% |
| Student > Master | 19 | 13% |
| Researcher | 16 | 11% |
| Student > Doctoral Student | 10 | 7% |
| Other | 9 | 6% |
| Other | 26 | 18% |
| Unknown | 27 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 25 | 18% |
| Neuroscience | 24 | 17% |
| Agricultural and Biological Sciences | 16 | 11% |
| Engineering | 12 | 9% |
| Psychology | 12 | 9% |
| Other | 22 | 16% |
| Unknown | 30 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 May 2013.
All research outputs
#17,285,036
of 25,371,288 outputs
Outputs from Neuropsychiatric Disease and Treatment
#1,901
of 3,132 outputs
Outputs of similar age
#129,685
of 204,326 outputs
Outputs of similar age from Neuropsychiatric Disease and Treatment
#33
of 53 outputs
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