Title |
Pediatric papillary thyroid cancer: current management challenges
|
---|---|
Published in |
OncoTargets and therapy, December 2016
|
DOI | 10.2147/ott.s100512 |
Pubmed ID | |
Authors |
Frederik A Verburg, Hanneke M Van Santen, Markus Luster |
Abstract |
Although with a standardized incidence of 0.54 cases per 100,000 persons, differentiated thyroid cancer (DTC) is a rare disease in children and adolescents, it nonetheless concerns ~1.4% of all pediatric malignancies. Furthermore, its incidence is rising. Due to the rarity and long survival of pediatric DTC patients, in most areas of treatment little evidence exists. Treatment of pediatric DTC is therefore littered with controversies, many questions therefore remain open regarding the optimal management of pediatric papillary thyroid cancer (PTC), and many challenges remain unsolved. In the present review, we aim to provide an overview of these challenging areas of patient and disease management in pediatric PTC patients. Data on diagnosis, surgery, radionuclide, and endocrine therapy are discussed, and the controversies therein are highlighted. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
China | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Portugal | 1 | 1% |
Unknown | 70 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 12 | 17% |
Student > Postgraduate | 11 | 15% |
Student > Bachelor | 10 | 14% |
Student > Master | 7 | 10% |
Student > Ph. D. Student | 6 | 8% |
Other | 12 | 17% |
Unknown | 13 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 40 | 56% |
Biochemistry, Genetics and Molecular Biology | 6 | 8% |
Psychology | 3 | 4% |
Nursing and Health Professions | 2 | 3% |
Immunology and Microbiology | 2 | 3% |
Other | 3 | 4% |
Unknown | 15 | 21% |