Title |
Hürthle cell carcinoma: current perspectives
|
---|---|
Published in |
OncoTargets and therapy, November 2016
|
DOI | 10.2147/ott.s119980 |
Pubmed ID | |
Authors |
Sara Ahmadi, Michael Stang, Xiaoyin “Sara” Jiang, Julie Ann Sosa |
Abstract |
Hürthle cell carcinoma (HCC) can present either as a minimally invasive or as a widely invasive tumor. HCC generally has a more aggressive clinical behavior compared with the other differentiated thyroid cancers, and it is associated with a higher rate of distant metastases. Minimally invasive HCC demonstrates much less aggressive behavior; lesions <4 cm can be treated with thyroid lobectomy alone, and without radioactive iodine (RAI). HCC has been observed to be less iodine-avid compared with other differentiated thyroid cancers; however, recent data have demonstrated improved survival with RAI use in patients with HCC >2 cm and those with nodal and distant metastases. Patients with localized iodine-resistant disease who are not candidates for a wait-and-watch approach can be treated with localized therapies. Systemic therapy is reserved for patients with progressive, widely metastatic HCC. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 7 | 23% |
India | 4 | 13% |
Turkey | 2 | 7% |
Myanmar | 2 | 7% |
Spain | 2 | 7% |
Bahrain | 1 | 3% |
Australia | 1 | 3% |
Unknown | 11 | 37% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 13 | 43% |
Practitioners (doctors, other healthcare professionals) | 9 | 30% |
Scientists | 6 | 20% |
Science communicators (journalists, bloggers, editors) | 2 | 7% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 90 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 11 | 12% |
Researcher | 11 | 12% |
Student > Bachelor | 11 | 12% |
Student > Doctoral Student | 8 | 9% |
Other | 8 | 9% |
Other | 17 | 19% |
Unknown | 24 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 41 | 46% |
Biochemistry, Genetics and Molecular Biology | 7 | 8% |
Agricultural and Biological Sciences | 4 | 4% |
Psychology | 2 | 2% |
Immunology and Microbiology | 2 | 2% |
Other | 4 | 4% |
Unknown | 30 | 33% |