| Title |
Association between adherence to medications for COPD and medications for other chronic conditions in COPD patients
|
|---|---|
| Published in |
International Journal of Chronic Obstructive Pulmonary Disease, December 2016
|
| DOI | 10.2147/copd.s114802 |
| Pubmed ID | |
| Authors |
Amol D Dhamane, Phil Schwab, Sari Hopson, Chad Moretz, Srinivas Annavarapu, Kate Burslem, Andrew Renda, Shuchita Kaila |
| Abstract |
Patients with COPD often have multiple comorbidities requiring use of multiple medications, and adherence rates for maintenance COPD (mCOPD) medications are already known to be suboptimal. Presence of comorbidities in COPD patients, and use of medications used to treat those comorbidities (non-COPD medications), may have an adverse impact on adherence to mCOPD medications. The objective of the study was to evaluate the association between non-adherence to mCOPD medications and non-COPD medications in COPD patients. COPD patients were identified using a large administrative claims database. Selected patients were 40-89 years old and continuously enrolled for 12 months prior to and 24 months after the first identified COPD diagnosis (index date) during January 1, 2009 to December 31, 2010. Patients were required to have ≥1 prescription for a mCOPD medication within 365 days of the index date and ≥1 prescription for one of 12 non-COPD medication classes within ±30 days of the first COPD prescription. Adherence (proportion of days covered [PDC]) was measured during 365 days following the first COPD prescription. The association between non-adherence (PDC <0.8) to mCOPD and non-adherence to non-COPD medications was determined using logistic regression, controlling for baseline patient characteristics. A total of 14,117 patients, with a mean age of 69.9 years, met study criteria. Of these, 40.9% were males and 79.2% were non-adherent to mCOPD medications with a mean PDC of 0.47. Non-adherence to mCOPD medications was associated with non-adherence to 10 of 12 non-COPD medication classes (odds ratio 1.38-1.78, all P<0.01). Adherence to mCOPD medications is low. Non-adherence (or adherence) to mCOPD medications is positively related to non-adherence (or adherence) to non-COPD medications, implying that the need to take medications prescribed for comorbid conditions does not adversely impact adherence to mCOPD medications. |
X Demographics
The data shown below were collected from the profiles of 41 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 12 | 29% |
| United States | 6 | 15% |
| Canada | 3 | 7% |
| Argentina | 2 | 5% |
| Venezuela, Bolivarian Republic of | 1 | 2% |
| Spain | 1 | 2% |
| Germany | 1 | 2% |
| India | 1 | 2% |
| Unknown | 14 | 34% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 28 | 68% |
| Practitioners (doctors, other healthcare professionals) | 12 | 29% |
| Science communicators (journalists, bloggers, editors) | 1 | 2% |
Mendeley readers
The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 65 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 14 | 22% |
| Student > Master | 8 | 12% |
| Researcher | 5 | 8% |
| Student > Postgraduate | 5 | 8% |
| Student > Ph. D. Student | 5 | 8% |
| Other | 13 | 20% |
| Unknown | 15 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 19 | 29% |
| Pharmacology, Toxicology and Pharmaceutical Science | 9 | 14% |
| Nursing and Health Professions | 9 | 14% |
| Agricultural and Biological Sciences | 3 | 5% |
| Economics, Econometrics and Finance | 2 | 3% |
| Other | 5 | 8% |
| Unknown | 18 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 454. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 January 2018.
All research outputs
#61,246
of 25,584,565 outputs
Outputs from International Journal of Chronic Obstructive Pulmonary Disease
#3
of 2,571 outputs
Outputs of similar age
#1,325
of 417,676 outputs
Outputs of similar age from International Journal of Chronic Obstructive Pulmonary Disease
#1
of 82 outputs
Altmetric has tracked 25,584,565 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,571 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one has done particularly well, scoring higher than 99% of its peers.
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We're also able to compare this research output to 82 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.