| Title |
Nanotechnology in the targeted drug delivery for bone diseases and bone regeneration
|
|---|---|
| Published in |
International Journal of Nanomedicine, June 2013
|
| DOI | 10.2147/ijn.s44393 |
| Pubmed ID | |
| Authors |
Wenyi Gu, Chengtie Wu, Jiezhong Chen, Yin Xiao |
| Abstract |
Nanotechnology is a vigorous research area and one of its important applications is in biomedical sciences. Among biomedical applications, targeted drug delivery is one of the most extensively studied subjects. Nanostructured particles and scaffolds have been widely studied for increasing treatment efficacy and specificity of present treatment approaches. Similarly, this technique has been used for treating bone diseases including bone regeneration. In this review, we have summarized and highlighted the recent advancement of nanostructured particles and scaffolds for the treatment of cancer bone metastasis, osteosarcoma, bone infections and inflammatory diseases, osteoarthritis, as well as for bone regeneration. Nanoparticles used to deliver deoxyribonucleic acid and ribonucleic acid molecules to specific bone sites for gene therapies are also included. The investigation of the implications of nanoparticles in bone diseases have just begun, and has already shown some promising potential. Further studies have to be conducted, aimed specifically at assessing targeted delivery and bioactive scaffolds to further improve their efficacy before they can be used clinically. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 4 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 4 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 250 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 2 | <1% |
| Turkey | 1 | <1% |
| Germany | 1 | <1% |
| South Africa | 1 | <1% |
| Unknown | 245 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 52 | 21% |
| Researcher | 32 | 13% |
| Student > Master | 30 | 12% |
| Student > Bachelor | 30 | 12% |
| Student > Doctoral Student | 15 | 6% |
| Other | 34 | 14% |
| Unknown | 57 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 32 | 13% |
| Pharmacology, Toxicology and Pharmaceutical Science | 29 | 12% |
| Agricultural and Biological Sciences | 24 | 10% |
| Medicine and Dentistry | 21 | 8% |
| Materials Science | 19 | 8% |
| Other | 55 | 22% |
| Unknown | 70 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 June 2023.
All research outputs
#2,267,307
of 25,584,565 outputs
Outputs from International Journal of Nanomedicine
#86
of 4,077 outputs
Outputs of similar age
#18,689
of 206,928 outputs
Outputs of similar age from International Journal of Nanomedicine
#1
of 63 outputs
Altmetric has tracked 25,584,565 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,077 research outputs from this source. They receive a mean Attention Score of 4.8. This one has done particularly well, scoring higher than 97% of its peers.
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We're also able to compare this research output to 63 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.