| Title |
Multimorbidity as specific disease combinations, an important predictor factor for mortality in octogenarians: the Octabaix study
|
|---|---|
| Published in |
Clinical Interventions in Aging, January 2017
|
| DOI | 10.2147/cia.s123173 |
| Pubmed ID | |
| Authors |
Assumpta Ferrer, Francesc Formiga, Héctor Sanz, Jesús Almeda, Glòria Padrós |
| Abstract |
The population is aging and multimorbidity is becoming a common problem in the elderly. To explore the effect of multimorbidity patterns on mortality for all causes at 3- and 5-year follow-up periods. A prospective community-based cohort (2009-2014) embedded within a randomized clinical trial was conducted in seven primary health care centers, including 328 subjects aged 85 years at baseline. Sociodemographic variables, sensory status, cardiovascular risk factors, comorbidity, and geriatric tests were analyzed. Multimorbidity patterns were defined as combinations of two or three of 16 specific chronic conditions in the same individual. Of the total sample, the median and interquartile range value of conditions was 4 (3-5). The individual morbidities significantly associated with death were chronic obstructive pulmonary disease (COPD; hazard ratio [HR]: 2.47; 95% confidence interval [CI]: 1.3; 4.7), atrial fibrillation (AF; HR: 2.41; 95% CI: 1.3; 4.3), and malignancy (HR: 1.9; 95% CI: 1.0; 3.6) at 3-year follow-up; whereas dementia (HR: 2.04; 95% CI: 1.3; 3.2), malignancy (HR: 1.84; 95% CI: 1.2; 2.8), and COPD (HR: 1.77; 95% CI: 1.1; 2.8) were the most associated with mortality at 5-year follow-up, after adjusting using Barthel functional index (BI). The two multimorbidity patterns most associated with death were AF, chronic kidney disease (CKD), and visual impairment (HR: 4.19; 95% CI: 2.2; 8.2) at 3-year follow-up as well as hypertension, CKD, and malignancy (HR: 3.24; 95% CI: 1.8; 5.8) at 5 years, after adjusting using BI. Multimorbidity as specific combinations of chronic conditions showed an effect on mortality, which would be higher than the risk attributable to individual morbidities. The most important predicting pattern for mortality was the combination of AF, CKD, and visual impairment after 3 years. These findings suggest that a new approach is required to target multimorbidity in octogenarians. |
X Demographics
The data shown below were collected from the profiles of 9 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 3 | 33% |
| Brazil | 1 | 11% |
| Australia | 1 | 11% |
| Canada | 1 | 11% |
| Unknown | 3 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 8 | 89% |
| Scientists | 1 | 11% |
Mendeley readers
The data shown below were compiled from readership statistics for 161 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 1 | <1% |
| Unknown | 160 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 25 | 16% |
| Student > Bachelor | 20 | 12% |
| Researcher | 19 | 12% |
| Student > Ph. D. Student | 14 | 9% |
| Student > Doctoral Student | 12 | 7% |
| Other | 30 | 19% |
| Unknown | 41 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 57 | 35% |
| Nursing and Health Professions | 18 | 11% |
| Social Sciences | 5 | 3% |
| Computer Science | 5 | 3% |
| Psychology | 3 | 2% |
| Other | 16 | 10% |
| Unknown | 57 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 May 2017.
All research outputs
#6,499,483
of 25,766,791 outputs
Outputs from Clinical Interventions in Aging
#604
of 1,979 outputs
Outputs of similar age
#108,456
of 424,052 outputs
Outputs of similar age from Clinical Interventions in Aging
#20
of 39 outputs
Altmetric has tracked 25,766,791 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 1,979 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.4. This one has gotten more attention than average, scoring higher than 69% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 424,052 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 39 others from the same source and published within six weeks on either side of this one. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.