Title |
Temperature- and pH-sensitive wearable materials for monitoring foot ulcers
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Published in |
International Journal of Nanomedicine, January 2017
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DOI | 10.2147/ijn.s121726 |
Pubmed ID | |
Authors |
Pietro Salvo, Nicola Calisi, Bernardo Melai, Valentina Dini, Clara Paoletti, Tommaso Lomonaco, Andrea Pucci, Fabio Di Francesco, Alberto Piaggesi, Marco Romanelli |
Abstract |
Foot ulcers account for 15% of comorbidities associated with diabetes. Presently, no device allows the status of foot ulcers to be continuously monitored when patients are not hospitalized. In this study, we describe a temperature and a pH sensor capable of monitoring diabetic foot and venous leg ulcers developed in the frame of the seventh framework program European Union project SWAN-iCare (smart wearable and autonomous negative pressure device for wound monitoring and therapy). Temperature is measured by exploiting the variations in the electrical resistance of a nanocomposite consisting of multiwalled carbon nanotubes and poly(styrene-b-(ethylene-co-butylene)-b-styrene). The pH sensor used a graphene oxide (GO) layer that changes its electrical potential when pH changes. The temperature sensor has a sensitivity of ~85 Ω/°C in the range 25°C-50°C and a high repeatability (maximum standard deviation of 0.1% over seven repeated measurements). For a GO concentration of 4 mg/mL, the pH sensor has a sensitivity of ~42 mV/pH and high linearity (R2=0.99). |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Spain | 1 | <1% |
United States | 1 | <1% |
Unknown | 144 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 23 | 16% |
Student > Ph. D. Student | 14 | 10% |
Other | 11 | 8% |
Researcher | 11 | 8% |
Student > Bachelor | 11 | 8% |
Other | 32 | 22% |
Unknown | 44 | 30% |
Readers by discipline | Count | As % |
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Engineering | 23 | 16% |
Medicine and Dentistry | 17 | 12% |
Nursing and Health Professions | 15 | 10% |
Chemistry | 10 | 7% |
Materials Science | 5 | 3% |
Other | 21 | 14% |
Unknown | 55 | 38% |