Title |
Harnessing supramolecular peptide nanotechnology in biomedical applications
|
---|---|
Published in |
International Journal of Nanomedicine, February 2017
|
DOI | 10.2147/ijn.s126154 |
Pubmed ID | |
Authors |
Kiat Hwa Chan, Wei Hao Lee, Shuangmu Zhuo, Ming Ni |
Abstract |
The harnessing of peptides in biomedical applications is a recent hot topic. This arises mainly from the general biocompatibility of peptides, as well as from the ease of tunability of peptide structure to engineer desired properties. The ease of progression from laboratory testing to clinical trials is evident from the plethora of examples available. In this review, we compare and contrast how three distinct self-assembled peptide nanostructures possess different functions. We have 1) nanofibrils in biomaterials that can interact with cells, 2) nanoparticles that can traverse the bloodstream to deliver its payload and also be bioimaged, and 3) nanotubes that can serve as cross-membrane conduits and as a template for nanowire formation. Through this review, we aim to illustrate how various peptides, in their various self-assembled nanostructures, possess great promise in a wide range of biomedical applications and what more can be expected. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 20% |
Mexico | 1 | 20% |
Unknown | 3 | 60% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 60% |
Scientists | 1 | 20% |
Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 50 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 13 | 26% |
Student > Bachelor | 7 | 14% |
Researcher | 6 | 12% |
Student > Doctoral Student | 3 | 6% |
Student > Master | 3 | 6% |
Other | 7 | 14% |
Unknown | 11 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Chemistry | 11 | 22% |
Biochemistry, Genetics and Molecular Biology | 9 | 18% |
Agricultural and Biological Sciences | 6 | 12% |
Medicine and Dentistry | 4 | 8% |
Engineering | 2 | 4% |
Other | 4 | 8% |
Unknown | 14 | 28% |