| Title |
Acceptability and efficacy of interactive short message service intervention in improving HIV medication adherence in Chinese antiretroviral treatment-naïve individuals
|
|---|---|
| Published in |
Patient preference and adherence, February 2017
|
| DOI | 10.2147/ppa.s120003 |
| Pubmed ID | |
| Authors |
Ye Ruan, Xueling Xiao, Jia Chen, Xianhong Li, Ann Bartley Williams, Honghong Wang |
| Abstract |
The aim of this study was to examine the acceptability and efficacy of interactive short message service (SMS) in improving medication adherence in antiretroviral treatment (ART)-naïve individuals living with HIV/AIDS in Hengyang, Hunan, China. SMS via mobile phone has emerged as a potential tool for improving ART adherence. However, most studies used SMS only as a medication reminder, with few studies exploring the effect of comprehensive, interactive SMS. In a randomized controlled trial, 100 HIV-positive patients on ART for <3 months were randomized into control or intervention arm. Participants in the control group received routine standard instruction for ART medication in the HIV clinics, while the intervention group received 6 months of an SMS intervention in addition to the standard care. A total of 124 text messages within 6 modules were edited, preinstalled, and sent to participants according to personalized schedules. Knowledge (of HIV and HIV medications), self-reported antiretroviral adherence (Visual Analog Scale [VAS] and Community Programs for Clinical Research on AIDS [CPCRA] Antiretroviral Medication Self-Report), and CD4 count were assessed at baseline and immediate post-intervention. Intervention participants were interviewed after completion of the study about their satisfaction with and acceptability of the SMS intervention. Baseline assessments were comparable between arms. Repeated-measures analysis showed that both HIV-related and ART medication knowledge of the intervention group showed better improvement over time than those of the control group after the intervention (P<0.0001). For the adherence measures, compared with the control group, participants in the intervention group had significantly higher VAS mean score (Z=2.735, P=0.006) and lower suboptimal adherence rate (Z=2.208, P=0.027) at the end of the study. The intervention had no effect on CD4 cell count. Almost all (96%) intervention participants reported satisfaction or high satisfaction with the SMS intervention, with 74% desiring to continue to receive the SMS intervention. The preferred frequency of messages was 1-2 messages per week. An interactive SMS intervention with comprehensive content shows promising efficacy in promoting medication adherence in ART-naïve individuals. Future work might further refine its ability to optimally tailor the intervention for individual preferences. |
X Demographics
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Papua New Guinea | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 136 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 136 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 28 | 21% |
| Researcher | 14 | 10% |
| Student > Ph. D. Student | 13 | 10% |
| Student > Postgraduate | 6 | 4% |
| Student > Doctoral Student | 6 | 4% |
| Other | 22 | 16% |
| Unknown | 47 | 35% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 28 | 21% |
| Nursing and Health Professions | 19 | 14% |
| Social Sciences | 7 | 5% |
| Biochemistry, Genetics and Molecular Biology | 4 | 3% |
| Economics, Econometrics and Finance | 4 | 3% |
| Other | 20 | 15% |
| Unknown | 54 | 40% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 May 2019.
All research outputs
#5,242,603
of 25,382,440 outputs
Outputs from Patient preference and adherence
#369
of 1,757 outputs
Outputs of similar age
#99,540
of 424,972 outputs
Outputs of similar age from Patient preference and adherence
#16
of 52 outputs
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