Title |
Amrubicin: potential in combination with cisplatin or carboplatin to treat small-cell lung cancer
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Published in |
Drug Design, Development and Therapy, August 2013
|
DOI | 10.2147/dddt.s41910 |
Pubmed ID | |
Authors |
Qian Ding, Jinbiao Zhan |
Abstract |
Small-cell lung cancer (SCLC) is the most aggressive form of lung cancer characterized by early metastasis and high mortality. In recent years, monotherapy and combination therapy of amrubicin with cisplatin or carboplatin has been actively studied and shown promise for the treatment of extensive disease SCLC (ED-SCLC). In this article, we summarize clinical trials of both monotherapy and combination therapy with amrubicin conducted in Japan, the USA, and the European Union. The results suggest that the clinical outcome of amrubicin therapy may be associated with genetic variations in patients. Further study of combination regimens in patients of different ethnicities is warranted. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 14 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 4 | 29% |
Student > Master | 3 | 21% |
Other | 2 | 14% |
Professor | 1 | 7% |
Student > Doctoral Student | 1 | 7% |
Other | 2 | 14% |
Unknown | 1 | 7% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 5 | 36% |
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 29% |
Agricultural and Biological Sciences | 2 | 14% |
Immunology and Microbiology | 1 | 7% |
Philosophy | 1 | 7% |
Other | 0 | 0% |
Unknown | 1 | 7% |