Title |
Oxidative damage parameters in renal tissues of aged and young rats based on gender
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Published in |
Clinical Interventions in Aging, June 2013
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DOI | 10.2147/cia.s46188 |
Pubmed ID | |
Authors |
Duygu Uzun, Gülcan Güntaş Korkmaz, Mustafa Erinç Sitar, Tamer Cebe, Karolin Yanar, Ufuk Çakatay, Seval Aydın |
Abstract |
Aging is characterized by a gradual functional decrease of all systems including the kidneys. Growing evidence links altered lipid protein redox-homeostasis with renal dysfunction. The effect of sexual dimorphism on the lipid protein redox-homeostasis mechanisms in the aging kidney is obscure. In the current study, we aimed to investigate redox homeostasis as it related to sexual dimorphism on protein oxidation and lipid peroxidation parameters, as protein carbonyl (PCO), total thiol (T-SH), advanced oxidation protein products (AOPP), malondialdehyde, glutathione (GSH), and superoxide dismutase (SOD) activity, as potential aging biomarkers, which may contribute to an analysis of the free radical theory of aging. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 25% |
Unknown | 3 | 75% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 2 | 50% |
Members of the public | 2 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 16 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 4 | 25% |
Student > Master | 3 | 19% |
Researcher | 3 | 19% |
Student > Doctoral Student | 2 | 13% |
Lecturer > Senior Lecturer | 1 | 6% |
Other | 3 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 5 | 31% |
Biochemistry, Genetics and Molecular Biology | 4 | 25% |
Arts and Humanities | 1 | 6% |
Unspecified | 1 | 6% |
Sports and Recreations | 1 | 6% |
Other | 2 | 13% |
Unknown | 2 | 13% |