Title |
Newly diagnosed congenital factor VII deficiency and utilization of recombinant activated factor VII (NovoSeven®)
|
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Published in |
Clinical Pharmacology : Advances and Applications, March 2013
|
DOI | 10.2147/cpaa.s39772 |
Pubmed ID | |
Authors |
Nicole S Bartosh, Tara Tomlin, Christian Cable, Kathleen Halka |
Abstract |
This case report presents a newly diagnosed congenital factor VII deficiency treated with recombinant activated factor VII (rFVIIa). Congenital factor VII deficiency is a rare autosomal-recessive bleeding disorder that occurs in fewer than 1/500,000 persons. Its presentation can vary from epistaxis to hemarthroses and severe central nervous system bleeding, and correlates poorly with factor VII levels. Our patient had not had a significant hemostatic challenge prior to his presentation and therefore never had any symptomatology suggestive of this disease. He was treated with rFVIIa, and was able to undergo repair of his fractures without bleeding. |
X Demographics
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United Kingdom | 1 | 100% |
Demographic breakdown
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
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Colombia | 1 | 5% |
Unknown | 21 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Postgraduate | 5 | 23% |
Student > Ph. D. Student | 4 | 18% |
Student > Bachelor | 2 | 9% |
Researcher | 2 | 9% |
Student > Master | 2 | 9% |
Other | 4 | 18% |
Unknown | 3 | 14% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 14 | 64% |
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Nursing and Health Professions | 1 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 5% |
Economics, Econometrics and Finance | 1 | 5% |
Other | 3 | 14% |
Unknown | 1 | 5% |