Title |
Role of leukotrienes in exercise-induced bronchoconstriction before and after a pilot rehabilitation training program
|
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Published in |
International Journal of General Medicine, July 2013
|
DOI | 10.2147/ijgm.s46953 |
Pubmed ID | |
Authors |
Ibrahim M El-Akkary, Zeinat El-Khouly Abdel-Fatah, Mervat El-Sayed El-Seweify, Gihan A El-Batouti, Ekhlas Abdel Aziz, Abdelnasser I Adam |
Abstract |
Whatever the initial stimulus for the exercise-induced bronchoconstriction (EIB) observed in asthmatic patients after exercise, the final effect is release of bronchoactive mediators, especially cysteinyl leukotrienes. Exercise rehabilitation training programs have been reported to protect against EIB. The exact mechanism(s) involved are not well understood. However, this protective effect may be related to adaptation and better coordination during exercise, depletion of cysteinyl leukotrienes, and/or a sluggish cysteinyl leukotriene response to exercise. The aim of the present work was to test the hypothesis that improvement in the incidence and severity of post-exercise bronchoconstriction after a rehabilitation training program is related to a change in leukotriene levels in response to exercise. |
X Demographics
Geographical breakdown
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 18 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 4 | 22% |
Student > Postgraduate | 3 | 17% |
Student > Bachelor | 2 | 11% |
Student > Master | 2 | 11% |
Professor | 1 | 6% |
Other | 2 | 11% |
Unknown | 4 | 22% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 7 | 39% |
Sports and Recreations | 4 | 22% |
Social Sciences | 2 | 11% |
Business, Management and Accounting | 1 | 6% |
Unknown | 4 | 22% |