Title |
Dissolving and biodegradable microneedle technologies for transdermal sustained delivery of drug and vaccine
|
---|---|
Published in |
Drug Design, Development and Therapy, September 2013
|
DOI | 10.2147/dddt.s44401 |
Pubmed ID | |
Authors |
Xiaoyun Hong, Liangming Wei, Fei Wu, Zaozhan Wu, Lizhu Chen, Zhenguo Liu, Weien Yuan |
Abstract |
Microneedles were first conceptualized for drug delivery many decades ago, overcoming the shortages and preserving the advantages of hypodermic needle and conventional transdermal drug-delivery systems to some extent. Dissolving and biodegradable microneedle technologies have been used for transdermal sustained deliveries of different drugs and vaccines. This review describes microneedle geometry and the representative dissolving and biodegradable microneedle delivery methods via the skin, followed by the fabricating methods. Finally, this review puts forward some perspectives that require further investigation. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 50% |
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | <1% |
India | 1 | <1% |
Poland | 1 | <1% |
Unknown | 303 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 57 | 19% |
Student > Ph. D. Student | 49 | 16% |
Student > Bachelor | 39 | 13% |
Researcher | 24 | 8% |
Student > Doctoral Student | 17 | 6% |
Other | 38 | 12% |
Unknown | 82 | 27% |
Readers by discipline | Count | As % |
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Pharmacology, Toxicology and Pharmaceutical Science | 59 | 19% |
Engineering | 45 | 15% |
Medicine and Dentistry | 24 | 8% |
Agricultural and Biological Sciences | 19 | 6% |
Chemistry | 16 | 5% |
Other | 47 | 15% |
Unknown | 96 | 31% |