Title |
Liposomal extended-release bupivacaine for postsurgical analgesia
|
---|---|
Published in |
Patient preference and adherence, September 2013
|
DOI | 10.2147/ppa.s32175 |
Pubmed ID | |
Authors |
Mark Lambrechts, Michael J O’Brien, Felix H Savoie, Zongbing You |
Abstract |
When physicians consider which analgesia to use postsurgery, the primary goal is to relieve pain with minimal adverse side effects. Bupivacaine, a commonly used analgesic, has been formulated into an aqueous suspension of multivesicular liposomes that provide long-lasting analgesia for up to 72 hours, while avoiding the adverse side effects of opioids. The increased efficacy of liposomal extended-release bupivacaine, compared to bupivacaine hydrochloride, has promoted its usage in a variety of surgeries including hemorrhoidectomy, bunionectomy, inguinal hernia repair, total knee arthroplasty, and augmentation mammoplasty. However, like other bupivacaine formulations, the liposomal extended-release bupivacaine does have some side effects. In this brief review, we provide an update of the current knowledge in the use of bupivacaine for postsurgical analgesia. |
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Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 2% |
Russia | 1 | 1% |
France | 1 | 1% |
Romania | 1 | 1% |
Unknown | 83 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 16 | 18% |
Student > Postgraduate | 10 | 11% |
Other | 9 | 10% |
Student > Master | 7 | 8% |
Student > Doctoral Student | 7 | 8% |
Other | 22 | 25% |
Unknown | 17 | 19% |
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Medicine and Dentistry | 36 | 41% |
Pharmacology, Toxicology and Pharmaceutical Science | 6 | 7% |
Agricultural and Biological Sciences | 5 | 6% |
Nursing and Health Professions | 4 | 5% |
Veterinary Science and Veterinary Medicine | 3 | 3% |
Other | 10 | 11% |
Unknown | 24 | 27% |