Title |
Cross-reactivity of human monoclonal antibodies generated with peripheral blood lymphocytes from dengue patients with Japanese encephalitis virus
|
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Published in |
Biologics: Targets & Therapy, August 2013
|
DOI | 10.2147/btt.s47438 |
Pubmed ID | |
Authors |
Chonlatip Pipattanaboon, Tadahiro Sasaki, Mitsuhiro Nishimura, Chayanee Setthapramote, Pannamthip Pitaksajjakul, Pornsawan Leaungwutiwong, Kriengsak Limkittikul, Orapim Puiprom, Mikiko Sasayama, Panjaporn Chaichana, Tamaki Okabayashi, Takeshi Kurosu, Ken-ichiro Ono, Pongrama Ramasoota, Kazuyoshi Ikuta |
Abstract |
Hybridomas that produce human monoclonal antibodies (HuMAbs) against Dengue virus (DV) had been prepared previously using peripheral blood lymphocytes from patients with DV during the acute and convalescent phases of a secondary infection. Anti-DV envelope glycoprotein (E) 99 clones, anti-DV premembrane protein (prM) 8 clones, and anti-DV nonstructural protein 1 (NS1) 4 clones were derived from four acute-phase patients, and anti-DV E 2 clones, anti-DV prM 2 clones, and anti-DV NS1 8 clones were derived from five convalescent-phase patients. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 1 | 3% |
Unknown | 31 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 7 | 22% |
Student > Ph. D. Student | 6 | 19% |
Unspecified | 3 | 9% |
Student > Master | 3 | 9% |
Student > Doctoral Student | 2 | 6% |
Other | 8 | 25% |
Unknown | 3 | 9% |
Readers by discipline | Count | As % |
---|---|---|
Immunology and Microbiology | 10 | 31% |
Medicine and Dentistry | 6 | 19% |
Unspecified | 3 | 9% |
Agricultural and Biological Sciences | 3 | 9% |
Environmental Science | 1 | 3% |
Other | 3 | 9% |
Unknown | 6 | 19% |