Title |
Current and emerging treatment options for uveal melanoma
|
---|---|
Published in |
Clinical Ophthalmology, August 2013
|
DOI | 10.2147/opth.s28863 |
Pubmed ID | |
Authors |
Patricia Rusa Pereira, Alexandre Nakao Odashiro, Li-Anne Lim, Cristina Miyamoto, Paula L Blanco, Macanori Odashiro, Shawn Maloney, Dominique F De Souza, Miguel N Burnier |
Abstract |
Uveal melanoma (UM) is the most common primary malignant intraocular tumor in adults, with a 10-year cumulative metastatic rate of 34%. The most common site of metastasis is the liver (95%). Unfortunately, the current treatment of metastatic UM is limited by the lack of effective systemic therapy. Options for the management of the primary intraocular tumor include radical surgery as well as conservative treatments in order to preserve visual acuity. For metastatic disease, several approaches have been described with no standard method. Nevertheless, median survival after liver metastasis is poor, being around 4-6 months, with a 1-year survival of 10%-15%. In this review, the authors summarize current and promising new treatments for UM. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 2% |
Netherlands | 1 | 1% |
Unknown | 93 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 20 | 21% |
Other | 13 | 14% |
Student > Bachelor | 13 | 14% |
Student > Master | 10 | 10% |
Student > Postgraduate | 8 | 8% |
Other | 14 | 15% |
Unknown | 18 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 52 | 54% |
Agricultural and Biological Sciences | 5 | 5% |
Biochemistry, Genetics and Molecular Biology | 4 | 4% |
Engineering | 4 | 4% |
Nursing and Health Professions | 2 | 2% |
Other | 7 | 7% |
Unknown | 22 | 23% |