| Title |
Review about gabapentin misuse, interactions, contraindications and side effects
|
|---|---|
| Published in |
Journal of experimental pharmacology, February 2017
|
| DOI | 10.2147/jep.s124391 |
| Pubmed ID | |
| Authors |
Gabriel C Quintero |
| Abstract |
The current work is targeted to review the risks of gabapentin misuse, its potential interactions with other drugs, side effects and use contraindications. This review consists of a total of 99 biographical references (from the year 1983 to 2016). A publication search of PubMed was performed from January 1983 to December 2016. It included animal studies, clinical studies, case studies and reviews related to gabapentin misuse, potential interactions, side effects and use contraindications. The search terms were gabapentin, anticonvulsant and antiepileptic. In general, it seems that gabapentin has risks of being misused based on the increased level of prescriptions, related fatalities, recreational misuse and higher doses of self-administration. The main reasons for gabapentin misuse are as follows: getting high, alleviating opioid withdrawal symptoms and potentiating methadone effects. Some of the main substances that interact with gabapentin are morphine, caffeine, losartan, ethacrynic acid, phenytoin, mefloquine and magnesium oxide. Some of the side effects caused by gabapentin are teratogenicity, hypoventilation, respiratory failure and myopathy. Finally, reports in general contraindicate the use of gabapentin in conditions such as myasthenia gravis and myoclonus. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Comoros | 1 | 33% |
| United States | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 2 | 67% |
| Members of the public | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 179 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 179 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 20 | 11% |
| Student > Bachelor | 18 | 10% |
| Student > Master | 17 | 9% |
| Student > Ph. D. Student | 16 | 9% |
| Other | 12 | 7% |
| Other | 33 | 18% |
| Unknown | 63 | 35% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 40 | 22% |
| Pharmacology, Toxicology and Pharmaceutical Science | 15 | 8% |
| Biochemistry, Genetics and Molecular Biology | 10 | 6% |
| Neuroscience | 9 | 5% |
| Nursing and Health Professions | 9 | 5% |
| Other | 30 | 17% |
| Unknown | 66 | 37% |
Attention Score in Context
This research output has an Altmetric Attention Score of 24. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 July 2023.
All research outputs
#1,550,792
of 25,382,440 outputs
Outputs from Journal of experimental pharmacology
#5
of 150 outputs
Outputs of similar age
#32,441
of 424,972 outputs
Outputs of similar age from Journal of experimental pharmacology
#1
of 4 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 150 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.8. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 424,972 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them