| Title |
Cost–utility analysis of prophylaxis versus treatment on demand in severe hemophilia A
|
|---|---|
| Published in |
ClinicoEconomics and Outcomes Research: CEOR, March 2011
|
| DOI | 10.2147/ceor.s16670 |
| Pubmed ID | |
| Authors |
Giorgio L Colombo, Sergio Di Matteo, Maria Elisa Mancuso, Elena Santagostino |
| Abstract |
Individuals with severe hemophilia A have reduced blood levels of clotting factor VIII (FVIII) leading to recurrent bleeding into joints and muscles. Primary prophylaxis with clotting factor concentrates started early in childhood prevents joint bleeds, thus avoiding joint damage and improving people's quality of life. There remain significant differences in the implementation of primary prophylaxis worldwide mainly due to the cost of prophylaxis compared with treatment on demand. |
Mendeley readers
The data shown below were compiled from readership statistics for 79 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | 1% |
| Canada | 1 | 1% |
| Brazil | 1 | 1% |
| Unknown | 76 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 18 | 23% |
| Student > Master | 10 | 13% |
| Student > Postgraduate | 7 | 9% |
| Student > Bachelor | 7 | 9% |
| Student > Ph. D. Student | 5 | 6% |
| Other | 17 | 22% |
| Unknown | 15 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 28 | 35% |
| Economics, Econometrics and Finance | 11 | 14% |
| Agricultural and Biological Sciences | 5 | 6% |
| Nursing and Health Professions | 4 | 5% |
| Biochemistry, Genetics and Molecular Biology | 3 | 4% |
| Other | 11 | 14% |
| Unknown | 17 | 22% |