| Title |
Effects of Caryota mitis profilin-loaded PLGA nanoparticles in a murine model of allergic asthma
|
|---|---|
| Published in |
International Journal of Nanomedicine, November 2013
|
| DOI | 10.2147/ijn.s51633 |
| Pubmed ID | |
| Authors |
Xiaojun Xiao, Xiaowei Zeng, Xinxin Zhang, Li Ma, Xiaoyu Liu, Haiqiong Yu, Lin Mei, Zhigang Liu |
| Abstract |
Pollen allergy is the most common allergic disease. However, tropical pollens, such as those of Palmae, have seldom been investigated compared with the specific immunotherapy studies done on hyperallergenic birch, olive, and ragweed pollens. Although poly(lactic-co-glycolic acid) (PLGA) has been extensively applied as a biodegradable polymer in medical devices, it has rarely been utilized as a vaccine adjuvant to prevent and treat allergic disease. In this study, we investigated the immunotherapeutic effects of recombinant Caryota mitis profilin (rCmP)-loaded PLGA nanoparticles and the underlying mechanisms involved. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 4 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 3 | 75% |
| Members of the public | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 2 | 4% |
| Unknown | 44 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 22% |
| Researcher | 7 | 15% |
| Student > Bachelor | 4 | 9% |
| Student > Doctoral Student | 3 | 7% |
| Professor | 3 | 7% |
| Other | 9 | 20% |
| Unknown | 10 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 7 | 15% |
| Medicine and Dentistry | 7 | 15% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 13% |
| Biochemistry, Genetics and Molecular Biology | 5 | 11% |
| Chemical Engineering | 3 | 7% |
| Other | 7 | 15% |
| Unknown | 11 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 June 2014.
All research outputs
#14,915,476
of 25,374,917 outputs
Outputs from International Journal of Nanomedicine
#1,586
of 4,122 outputs
Outputs of similar age
#120,142
of 226,637 outputs
Outputs of similar age from International Journal of Nanomedicine
#34
of 97 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,122 research outputs from this source. They receive a mean Attention Score of 4.7. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,637 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 97 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.