Title |
Serum proteomic study on EGFR-TKIs target treatment for patients with NSCLC
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Published in |
OncoTargets and therapy, October 2013
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DOI | 10.2147/ott.s51887 |
Pubmed ID | |
Authors |
Xuan Wu, Wenhua Liang, Xue Hou, Zhong Lin, Hongyun Zhao, Yan Huang, Wenfeng Fang, Yuanyuan Zhao, Jingxun Wu, Yunpeng Yang, Chong Xue, Zhihuang Hu, Jing Zhang, Jianwei Zhang, Yuxiang Ma, Ting Zhou, Tao Qin, Li Zhang |
Abstract |
Although epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) are widely used for EGFR mutated non-small-cell lung cancer (NSCLC) patients, tumor sample availability and heterogeneity of the tumor remain challenging for physicians' selection of these patients. Here, we developed a serum proteomic classifier based on matrix assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF-MS) to predict the clinical outcome of patients treated with EGFR-TKIs. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 19 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 5 | 26% |
Other | 4 | 21% |
Student > Bachelor | 3 | 16% |
Researcher | 2 | 11% |
Student > Doctoral Student | 1 | 5% |
Other | 3 | 16% |
Unknown | 1 | 5% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 7 | 37% |
Biochemistry, Genetics and Molecular Biology | 2 | 11% |
Agricultural and Biological Sciences | 2 | 11% |
Engineering | 2 | 11% |
Physics and Astronomy | 1 | 5% |
Other | 3 | 16% |
Unknown | 2 | 11% |