Title |
Management of hypoactive sexual desire disorder in women: current and emerging therapies
|
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Published in |
International Journal of Women's Health, July 2010
|
DOI | 10.2147/ijwh.s7578 |
Pubmed ID | |
Authors |
Rossella E Nappi, Ellis Martini, Erica Terreno, Francesca Albani, Valentina Santamaria, Silvia Tonani, Luca Chiovato, Franco Polatti |
Abstract |
Hypoactive sexual desire disorder (HSDD) is a common multifactorial condition which is characterized by a decrease in sexual desire that causes marked personal distress and/or interpersonal difficulty. The general idea that HSDD is a sexual dysfunction difficult to treat is due to the large number of potential causes and contributing factors. Indeed, a balanced approach comprising both biological and psycho-relational factors is mandatory for accurate diagnosis and tailored management in clinical practice. There are currently no approved pharmacological treatments for premenopausal women with HSDD, while transdermal testosterone is approved in Europe for postmenopausal women who experience HSDD as a result of a bilateral oophorectomy. Even though the role of sex hormones in modulating the sexual response during the entire reproductive life span of women is crucial, a better understanding of the neurobiological basis of sexual desire supports the idea that selective psychoactive agents may be proposed as nonhormonal treatments to restore the balance between excitatory and inhibitory stimuli leading to a normal sexual response cycle. We conclude that the ideal clinical approach to HSDD remains to be established in term of efficacy and safety, and further research is needed to develop specific hormonal and nonhormonal pharmacotherapies for individualized care in women. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Sweden | 1 | 50% |
United States | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 60 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 13 | 22% |
Other | 11 | 18% |
Student > Ph. D. Student | 6 | 10% |
Researcher | 5 | 8% |
Student > Master | 5 | 8% |
Other | 8 | 13% |
Unknown | 12 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 28 | 47% |
Psychology | 7 | 12% |
Agricultural and Biological Sciences | 2 | 3% |
Nursing and Health Professions | 2 | 3% |
Computer Science | 1 | 2% |
Other | 8 | 13% |
Unknown | 12 | 20% |