| Title |
Complex management of a patient with refractory primary erythromelalgia lacking a SCN9A mutation
|
|---|---|
| Published in |
Journal of Pain Research, April 2017
|
| DOI | 10.2147/jpr.s129661 |
| Pubmed ID | |
| Authors |
Sarah A Low, Wendye Robbins, Vivianne L Tawfik |
| Abstract |
A 41-year-old woman presented with burning and erythema in her extremities triggered by warmth and activity, which was relieved by applying ice. Extensive workup was consistent with adult-onset primary erythromelalgia (EM). Several pharmacological treatments were tried including local anesthetics, capsaicin, ziconotide, and dantrolene, all providing 24-48 hours of relief followed by symptom flare. Interventional therapies, including peripheral and sympathetic ganglion blocks, also failed. Thus far, clonidine and ketamine have been the only effective agents for our patient. Genetic testing was negative for an EM-associated mutation in the SCN9A gene, encoding the NaV1.7 sodium channel, suggesting a mutation in an alternate gene. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 3 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 22 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 4 | 18% |
| Student > Postgraduate | 2 | 9% |
| Researcher | 2 | 9% |
| Student > Doctoral Student | 2 | 9% |
| Unspecified | 1 | 5% |
| Other | 2 | 9% |
| Unknown | 9 | 41% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 7 | 32% |
| Engineering | 2 | 9% |
| Neuroscience | 2 | 9% |
| Psychology | 1 | 5% |
| Unspecified | 1 | 5% |
| Other | 1 | 5% |
| Unknown | 8 | 36% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 August 2019.
All research outputs
#12,976,301
of 22,968,808 outputs
Outputs from Journal of Pain Research
#842
of 1,757 outputs
Outputs of similar age
#148,523
of 309,601 outputs
Outputs of similar age from Journal of Pain Research
#39
of 65 outputs
Altmetric has tracked 22,968,808 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,757 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.0. This one has gotten more attention than average, scoring higher than 51% of its peers.
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We're also able to compare this research output to 65 others from the same source and published within six weeks on either side of this one. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.