Title |
Effects of Phyllanthus emblica extract on endothelial dysfunction and biomarkers of oxidative stress in patients with type 2 diabetes mellitus: a randomized, double-blind, controlled study
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Published in |
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, July 2013
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DOI | 10.2147/dmso.s46341 |
Pubmed ID | |
Authors |
Pingali Usharani, Nishat Fatima, Nizampatnam Muralidhar |
Abstract |
It has been reported that hyperglycemia can induce endothelial dysfunction via increased oxidative stress and that it plays a central role in the development of atherosclerosis and coronary heart disease. Phyllanthus emblica (Emblica officinalis, amla) is known for its antioxidant and antihyperlipidemic activity. The present study compared the effects of an aqueous extract of P. emblica (highly standardized by high-performance liquid chromatography to contain low molecular weight hydrolyzable tannins, ie, emblicanin A, emblicanin B, pedunculagin, and punigluconin) versus those of atorvastatin and placebo on endothelial dysfunction and biomarkers of oxidative stress in patients with type 2 diabetes. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 1 | 20% |
United Kingdom | 1 | 20% |
United States | 1 | 20% |
Canada | 1 | 20% |
Unknown | 1 | 20% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 2 | 40% |
Members of the public | 2 | 40% |
Scientists | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Indonesia | 1 | 1% |
United States | 1 | 1% |
Unknown | 97 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 16 | 16% |
Researcher | 13 | 13% |
Student > Master | 11 | 11% |
Student > Bachelor | 11 | 11% |
Student > Doctoral Student | 9 | 9% |
Other | 17 | 17% |
Unknown | 22 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 24 | 24% |
Agricultural and Biological Sciences | 12 | 12% |
Pharmacology, Toxicology and Pharmaceutical Science | 10 | 10% |
Biochemistry, Genetics and Molecular Biology | 9 | 9% |
Chemistry | 5 | 5% |
Other | 10 | 10% |
Unknown | 29 | 29% |