Title |
Overview of diagnostic/targeted treatment combinations in personalized medicine for breast cancer patients
|
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Published in |
Pharmacogenomics and Personalized Medicine, December 2013
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DOI | 10.2147/pgpm.s53304 |
Pubmed ID | |
Authors |
Anna Tessari, Dario Palmieri, Serena Di Cosimo |
Abstract |
Breast cancer includes a body of molecularly distinct subgroups, characterized by different presentation, prognosis, and sensitivity to treatments. Significant advances in our understanding of the complex architecture of this pathology have been achieved in the last few decades, thanks to new biotechnologies that have recently come into the research field and the clinical practice, giving oncologists new instruments that are based on biomarkers and allowing them to set up a personalized approach for each individual patient. Here we review the main treatments available or in preclinical development, the biomolecular diagnostic and prognostic approaches that changed our perspective about breast cancer, giving an overview of targeted therapies that represent the current standard of care for these patients. Finally, we report some examples of how new technologies in clinical practice can set in motion the development of new drugs. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 2% |
Russia | 1 | 2% |
Brazil | 1 | 2% |
Unknown | 44 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 10 | 21% |
Student > Master | 8 | 17% |
Student > Postgraduate | 6 | 13% |
Researcher | 5 | 11% |
Student > Bachelor | 3 | 6% |
Other | 8 | 17% |
Unknown | 7 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 13 | 28% |
Agricultural and Biological Sciences | 8 | 17% |
Biochemistry, Genetics and Molecular Biology | 7 | 15% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 6% |
Chemistry | 2 | 4% |
Other | 6 | 13% |
Unknown | 8 | 17% |