| Title |
Neutralizing antibodies to botulinum neurotoxin type A in aesthetic medicine: five case reports
|
|---|---|
| Published in |
Clinical, Cosmetic and Investigational Dermatology, December 2013
|
| DOI | 10.2147/ccid.s51938 |
| Pubmed ID | |
| Authors |
Sebastian Torres, Mark Hamilton, Elena Sanches, Polina Starovatova, Elena Gubanova, Tatiana Reshetnikova |
| Abstract |
Botulinum neurotoxin injections are a valuable treatment modality for many therapeutic indications as well as in the aesthetic field for facial rejuvenation. As successful treatment requires repeated injections over a long period of time, secondary resistance to botulinum toxin preparations after repeated injections is an ongoing concern. We report five case studies in which neutralizing antibodies to botulinum toxin type A developed after injection for aesthetic use and resulted in secondary treatment failure. These results add to the growing number of reports in the literature for secondary treatment failure associated with high titers of neutralizing antibodies in the aesthetic field. Clinicians should be aware of this risk and implement injection protocols that minimize resistance development. |
X Demographics
The data shown below were collected from the profiles of 3,513 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Thailand | 397 | 11% |
| United States | 21 | <1% |
| United Kingdom | 16 | <1% |
| France | 12 | <1% |
| Japan | 11 | <1% |
| Bosnia and Herzegovina | 11 | <1% |
| Sri Lanka | 9 | <1% |
| Korea, Republic of | 8 | <1% |
| Central African Republic | 8 | <1% |
| Other | 51 | 1% |
| Unknown | 2969 | 85% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3504 | 100% |
| Practitioners (doctors, other healthcare professionals) | 6 | <1% |
| Scientists | 2 | <1% |
| Science communicators (journalists, bloggers, editors) | 1 | <1% |
Mendeley readers
The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 52 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 6 | 12% |
| Student > Bachelor | 6 | 12% |
| Student > Postgraduate | 5 | 10% |
| Student > Master | 5 | 10% |
| Student > Doctoral Student | 3 | 6% |
| Other | 14 | 27% |
| Unknown | 13 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 20 | 38% |
| Agricultural and Biological Sciences | 5 | 10% |
| Biochemistry, Genetics and Molecular Biology | 4 | 8% |
| Nursing and Health Professions | 1 | 2% |
| Immunology and Microbiology | 1 | 2% |
| Other | 5 | 10% |
| Unknown | 16 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 296. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 September 2022.
All research outputs
#120,940
of 25,909,281 outputs
Outputs from Clinical, Cosmetic and Investigational Dermatology
#18
of 924 outputs
Outputs of similar age
#997
of 323,258 outputs
Outputs of similar age from Clinical, Cosmetic and Investigational Dermatology
#1
of 10 outputs
Altmetric has tracked 25,909,281 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 924 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 23.3. This one has done particularly well, scoring higher than 98% of its peers.
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