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Advances in gene therapy technologies to treat retinitis pigmentosa

Overview of attention for article published in Clinical Ophthalmology, December 2013
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (75th percentile)
  • High Attention Score compared to outputs of the same age and source (94th percentile)

Mentioned by

twitter
3 tweeters
patent
1 patent
facebook
1 Facebook page

Citations

dimensions_citation
57 Dimensions

Readers on

mendeley
119 Mendeley
Title
Advances in gene therapy technologies to treat retinitis pigmentosa
Published in
Clinical Ophthalmology, December 2013
DOI 10.2147/opth.s38041
Pubmed ID
Authors

Hilda Petrs-Silva, Rafael Linden

Abstract

Retinitis pigmentosa (RP) is a class of diseases that leads to progressive degeneration of the retina. Experimental approaches to gene therapy for the treatment of inherited retinal dystrophies have advanced in recent years, inclusive of the safe delivery of genes to the human retina. This review is focused on the development of gene therapy for RP using recombinant adenoassociated viral vectors, which show a positive safety record and have so far been successful in several clinical trials for congenital retinal disease. Gene therapy for RP is under development in a variety of animal models, and the results raise expectations of future clinical application. Nonetheless, the translation of such strategies to the bedside requires further understanding of the mutations and mechanisms that cause visual defects, as well as thorough examination of potential adverse effects.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 119 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 119 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 22 18%
Student > Bachelor 20 17%
Student > Master 18 15%
Researcher 14 12%
Student > Doctoral Student 7 6%
Other 25 21%
Unknown 13 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 28 24%
Medicine and Dentistry 25 21%
Neuroscience 16 13%
Biochemistry, Genetics and Molecular Biology 15 13%
Engineering 5 4%
Other 12 10%
Unknown 18 15%

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 May 2020.
All research outputs
#4,705,049
of 17,697,618 outputs
Outputs from Clinical Ophthalmology
#315
of 2,560 outputs
Outputs of similar age
#66,127
of 275,142 outputs
Outputs of similar age from Clinical Ophthalmology
#5
of 90 outputs
Altmetric has tracked 17,697,618 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 2,560 research outputs from this source. They receive a mean Attention Score of 3.6. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 275,142 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 75% of its contemporaries.
We're also able to compare this research output to 90 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.