Title |
Gastroparesis: a review of current and emerging treatment options
|
---|---|
Published in |
Clinical and Experimental Gastroenterology, September 2013
|
DOI | 10.2147/ceg.s50236 |
Pubmed ID | |
Authors |
Chijioke Enweluzo, Fahad Aziz |
Abstract |
Gastroparesis is a motility disorder of the stomach causing delay in food emptying from the stomach without any evidence of mechanical obstruction. The majority of cases are idiopathic. Patients need to be diagnosed properly by formal testing, and the evaluation of the severity of the gastroparesis may assist in guiding therapy. Initially, dietary modifications are encouraged, which include frequent and small semisolid-based meals. Promotility medications, like erythromycin, and antiemetics, like prochlorperazine, are offered for symptom relief. In patients who are refractory to pharmacologic treatment, more invasive options, such as intrapyloric botulinum toxin injections, placement of a jejunostomy tube, or implantation of a gastric stimulator, can be considered. Hemin therapy and gastric electric stimulation are emerging treatment options that are still at different stages of research. Regenerative medicine and stem cell-based therapies also hold promise for gastroparesis in the near future. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 20% |
Romania | 1 | 20% |
Belgium | 1 | 20% |
Unknown | 2 | 40% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 60% |
Scientists | 1 | 20% |
Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 54 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Postgraduate | 10 | 19% |
Researcher | 7 | 13% |
Student > Doctoral Student | 7 | 13% |
Student > Bachelor | 6 | 11% |
Student > Ph. D. Student | 6 | 11% |
Other | 11 | 20% |
Unknown | 7 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 32 | 59% |
Engineering | 2 | 4% |
Agricultural and Biological Sciences | 2 | 4% |
Nursing and Health Professions | 1 | 2% |
Biochemistry, Genetics and Molecular Biology | 1 | 2% |
Other | 5 | 9% |
Unknown | 11 | 20% |