Title |
Epilepsy and suicide: pathogenesis, risk factors, and prevention
|
---|---|
Published in |
Neuropsychiatric Disease and Treatment, April 2008
|
DOI | 10.2147/ndt.s2158 |
Pubmed ID | |
Authors |
Alberto Verrotti, Alessandra Cicconetti, Barbara Scorrano, Domenico De Berardis, Carla Cotellessa, Francesco Chiarelli, Filippo Maria Ferro |
Abstract |
Depression and suicide tendencies are common in chronic diseases, especially in epilepsy and diabetes. Suicide is one of the most important causes of death, and is usually underestimated. We have analyzed several studies that compare mortality as a result of suicide in epileptic patients and in the general population. All the studies show that epileptic patients have a stronger tendency toward suicide than healthy controls. Moreover it seems that some kinds of epilepsy have a higher risk for suicide (temporal-lobe epilepsy). Among the risk factors are surgery therapy (suicide tendency five times higher than patients in pharmacological therapy), absence of seizures for a long time, especially after being very frequent, and psychiatric comorbidity (major depression, anxiety-depression disorders, personality disorders, substance abuse, psychoses). The aim of the review was to analyze the relationship between suicide and epilepsy, to identify the major risk factors, and to analyze effective treatment options. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 3 | 25% |
United States | 1 | 8% |
Unknown | 8 | 67% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 12 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 1% |
Nigeria | 1 | 1% |
Canada | 1 | 1% |
Unknown | 86 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 14 | 16% |
Student > Ph. D. Student | 13 | 15% |
Researcher | 11 | 12% |
Student > Postgraduate | 7 | 8% |
Student > Doctoral Student | 4 | 4% |
Other | 22 | 25% |
Unknown | 18 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 40 | 45% |
Psychology | 12 | 13% |
Neuroscience | 7 | 8% |
Agricultural and Biological Sciences | 3 | 3% |
Immunology and Microbiology | 2 | 2% |
Other | 7 | 8% |
Unknown | 18 | 20% |