Title |
Developmental and behavioral outcomes of uncomplicated monochorionic diamniotic twins born in the third trimester
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Published in |
Neuropsychiatric Disease and Treatment, May 2017
|
DOI | 10.2147/ndt.s122739 |
Pubmed ID | |
Authors |
Amy Sierakowski, Valsamma Eapen, Rudi Črnčec, John Smoleniec |
Abstract |
Relatively little is known about the neurodevelopmental and behavioral outcomes of monochorionic diamniotic (MCDA) twin pregnancies where there are no antenatal complications peculiar to monochorionicity or prematurity. Twenty-two MCDA twins (44 children) with an average age of 4.3 years, and with no antenatal complications detected by 28 weeks of gestation, were recruited from a feto-maternal unit database. Parents completed a battery of neurodevelopmental and behavioral assessment questionnaires. Eighteen children (41%) were identified as having developmental or behavioral concerns, predominantly of mild severity, which in turn were associated with a lower birth weight of medium effect size (Cohen's d=0.59). MCDA twins delivered in the third trimester with no antenatal monochorionic complications in the first two trimesters appear to be at risk for subtle neurodevelopmental difficulties, associated with a lower birth weight. Ongoing developmental surveillance of these children during preschool-age is indicated for early identification and intervention. |
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