| Title |
Possible association between haplotypes of the FKBP5 gene and suicidal bipolar disorder, but not with melancholic depression and psychotic features, in the course of bipolar disorder
|
|---|---|
| Published in |
Neuropsychiatric Disease and Treatment, February 2014
|
| DOI | 10.2147/ndt.s54538 |
| Pubmed ID | |
| Authors |
Anna Leszczyńska-Rodziewicz, Aleksandra Szczepankiewicz, Beata Narożna, Maria Skibińska, Joanna Pawlak, Monika Dmitrzak-Węglarz, Joanna Hauser |
| Abstract |
We aimed to analyzed the association between polymorphisms of the FKBP5 (FK506 binding protein 5) gene and subtypes of bipolar disorder. In the study, we included 195 bipolar disorder patients with psychotic features, 129 bipolar patients with melancholic depression, and 156 bipolar patients with a history of suicidal attempts. We found weak association between the haplotypes of the FKBP5 gene and bipolar patients with suicidal attempts. We did not find an association between polymorphisms of the FKBP5 gene and bipolar disorder with psychotic features, nor with bipolar disorder with melancholic depression. Limitations of our study are the absence of data about previous trauma exposure and the small sample size of patients, which of course can lead to false-positive results, so further validation and replication of the present findings are still needed. |
X Demographics
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 48 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 6 | 13% |
| Student > Bachelor | 6 | 13% |
| Student > Doctoral Student | 6 | 13% |
| Student > Ph. D. Student | 4 | 8% |
| Student > Master | 4 | 8% |
| Other | 9 | 19% |
| Unknown | 13 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 8 | 17% |
| Medicine and Dentistry | 6 | 13% |
| Agricultural and Biological Sciences | 5 | 10% |
| Neuroscience | 4 | 8% |
| Unspecified | 3 | 6% |
| Other | 6 | 13% |
| Unknown | 16 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 February 2014.
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#22,759,452
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Outputs from Neuropsychiatric Disease and Treatment
#2,584
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#282,808
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Outputs of similar age from Neuropsychiatric Disease and Treatment
#57
of 58 outputs
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