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Possible association between haplotypes of the FKBP5 gene and suicidal bipolar disorder, but not with melancholic depression and psychotic features, in the course of bipolar disorder

Overview of attention for article published in Neuropsychiatric Disease and Treatment, February 2014
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Title
Possible association between haplotypes of the FKBP5 gene and suicidal bipolar disorder, but not with melancholic depression and psychotic features, in the course of bipolar disorder
Published in
Neuropsychiatric Disease and Treatment, February 2014
DOI 10.2147/ndt.s54538
Pubmed ID
Authors

Anna Leszczyńska-Rodziewicz, Aleksandra Szczepankiewicz, Maria Skibińska, Joanna Pawlak, Monika Dmitrzak-Węglarz, Joanna Hauser, Beata Narozna

Abstract

We aimed to analyzed the association between polymorphisms of the FKBP5 (FK506 binding protein 5) gene and subtypes of bipolar disorder. In the study, we included 195 bipolar disorder patients with psychotic features, 129 bipolar patients with melancholic depression, and 156 bipolar patients with a history of suicidal attempts. We found weak association between the haplotypes of the FKBP5 gene and bipolar patients with suicidal attempts. We did not find an association between polymorphisms of the FKBP5 gene and bipolar disorder with psychotic features, nor with bipolar disorder with melancholic depression. Limitations of our study are the absence of data about previous trauma exposure and the small sample size of patients, which of course can lead to false-positive results, so further validation and replication of the present findings are still needed.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 38 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 6 16%
Researcher 6 16%
Student > Master 5 13%
Student > Bachelor 5 13%
Student > Ph. D. Student 4 11%
Other 5 13%
Unknown 7 18%
Readers by discipline Count As %
Psychology 9 24%
Medicine and Dentistry 6 16%
Agricultural and Biological Sciences 5 13%
Neuroscience 2 5%
Social Sciences 2 5%
Other 4 11%
Unknown 10 26%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 February 2014.
All research outputs
#12,841,405
of 14,535,828 outputs
Outputs from Neuropsychiatric Disease and Treatment
#1,988
of 2,442 outputs
Outputs of similar age
#207,545
of 250,045 outputs
Outputs of similar age from Neuropsychiatric Disease and Treatment
#85
of 96 outputs
Altmetric has tracked 14,535,828 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,442 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 250,045 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 96 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.