Title |
Prioritizing single-nucleotide polymorphisms and variants associated with clinical mastitis
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Published in |
Advances and Applications in Bioinformatics and Chemistry : AABC, June 2017
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DOI | 10.2147/aabc.s123604 |
Pubmed ID | |
Authors |
Prashanth Suravajhala, Alfredo Benso |
Abstract |
Next-generation sequencing technology has provided resources to easily explore and identify candidate single-nucleotide polymorphisms (SNPs) and variants. However, there remains a challenge in identifying and inferring the causal SNPs from sequence data. A problem with different methods that predict the effect of mutations is that they produce false positives. In this hypothesis, we provide an overview of methods known for identifying causal variants and discuss the challenges, fallacies, and prospects in discerning candidate SNPs. We then propose a three-point classification strategy, which could be an additional annotation method in identifying causalities. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 2 | 67% |
Taiwan | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 2 | 67% |
Members of the public | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 21 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 6 | 29% |
Student > Ph. D. Student | 4 | 19% |
Student > Bachelor | 3 | 14% |
Other | 1 | 5% |
Student > Master | 1 | 5% |
Other | 1 | 5% |
Unknown | 5 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 6 | 29% |
Agricultural and Biological Sciences | 4 | 19% |
Computer Science | 2 | 10% |
Mathematics | 1 | 5% |
Veterinary Science and Veterinary Medicine | 1 | 5% |
Other | 2 | 10% |
Unknown | 5 | 24% |