Title |
Efficacy and safety of febuxostat in the treatment of hyperuricemia in stable kidney transplant recipients
|
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Published in |
Drug Design, Development and Therapy, February 2014
|
DOI | 10.2147/dddt.s56597 |
Pubmed ID | |
Authors |
Tadashi Sofue, Masashi Inui, Taiga Hara, Yoko Nishijima, Kumiko Moriwaki, Yushi Hayashida, Nobufumi Ueda, Akira Nishiyama, Yoshiyuki Kakehi, Masakazu Kohno |
Abstract |
Post-transplant hyperuricemia (PTHU), defined as serum uric acid concentration ≥7.0 mg/dL or need for treatment with allopurinol or benzbromarone, reduces long-term allograft survival in kidney transplant recipients. Febuxostat, a new nonpurine selective xanthine oxidase inhibitor, is well tolerated in patients with moderate renal impairment. However, its efficacy and safety in kidney recipients with PTHU is unclear. We therefore assessed the efficacy and safety of febuxostat in stable kidney transplant recipients with PTHU. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 28 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 9 | 32% |
Other | 3 | 11% |
Student > Ph. D. Student | 3 | 11% |
Student > Bachelor | 2 | 7% |
Professor | 2 | 7% |
Other | 6 | 21% |
Unknown | 3 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 15 | 54% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 18% |
Nursing and Health Professions | 1 | 4% |
Social Sciences | 1 | 4% |
Psychology | 1 | 4% |
Other | 0 | 0% |
Unknown | 5 | 18% |