Title |
Aging differentially affects male and female neural stem cell neurogenic properties
|
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Published in |
Stem cells and cloning advances and applications, September 2010
|
DOI | 10.2147/sccaa.s13035 |
Pubmed ID | |
Authors |
Jay Waldron, Althea McCourty, Laurent Lecanu |
Abstract |
Neural stem cell transplantation as a brain repair strategy is a very promising technology. However, despite many attempts, the clinical success remains very deceiving. Despite clear evidence that sexual dimorphism rules many aspects of human biology, the occurrence of a sex difference in neural stem cell biology is largely understudied. Herein, we propose to determine whether gender is a dimension that drives the fate of neural stem cells through aging. Should it occur, we believe that neural stem cell sexual dimorphism and its variation during aging should be taken into account to refine clinical approaches of brain repair strategies. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 7% |
Unknown | 27 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 7 | 24% |
Student > Bachelor | 5 | 17% |
Researcher | 5 | 17% |
Professor | 3 | 10% |
Student > Master | 2 | 7% |
Other | 1 | 3% |
Unknown | 6 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 8 | 28% |
Neuroscience | 6 | 21% |
Biochemistry, Genetics and Molecular Biology | 5 | 17% |
Social Sciences | 1 | 3% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
Other | 2 | 7% |
Unknown | 6 | 21% |