| Title |
The role of microglia in multiple sclerosis
|
|---|---|
| Published in |
Neuropsychiatric Disease and Treatment, June 2017
|
| DOI | 10.2147/ndt.s140634 |
| Pubmed ID | |
| Authors |
Chun Luo, Chongdong Jian, Yuhan Liao, Qi Huang, Yuejuan Wu, Xixia Liu, Donghua Zou, Yuan Wu |
| Abstract |
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS). Microglia are the resident innate immune cells in the CNS; they play an important role in the processes of demyelination and remyelination in MS. Microglia can function as antigen-presenting cells and phagocytes. In the past, microglia were considered to be the same cell type as macrophages, and researchers have different opinions about the role of microglia in MS. This review focuses on the original classification of microglia and their role in the pathogenesis of MS. Moreover, we present a hypothetical model for the role of microglia in the pathogenesis of MS based on recent findings. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 3 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 380 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 380 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 86 | 23% |
| Student > Ph. D. Student | 56 | 15% |
| Student > Master | 47 | 12% |
| Researcher | 30 | 8% |
| Student > Doctoral Student | 18 | 5% |
| Other | 37 | 10% |
| Unknown | 106 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 61 | 16% |
| Biochemistry, Genetics and Molecular Biology | 56 | 15% |
| Agricultural and Biological Sciences | 45 | 12% |
| Medicine and Dentistry | 34 | 9% |
| Immunology and Microbiology | 17 | 4% |
| Other | 41 | 11% |
| Unknown | 126 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 102. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 June 2023.
All research outputs
#414,336
of 25,382,440 outputs
Outputs from Neuropsychiatric Disease and Treatment
#47
of 3,131 outputs
Outputs of similar age
#8,680
of 330,503 outputs
Outputs of similar age from Neuropsychiatric Disease and Treatment
#2
of 85 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,131 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.6. This one has done particularly well, scoring higher than 98% of its peers.
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We're also able to compare this research output to 85 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.