| Title |
Regular physical exercise improves cardiac autonomic and muscle vasodilatory responses to isometric exercise in healthy elderly
|
|---|---|
| Published in |
Clinical Interventions in Aging, June 2017
|
| DOI | 10.2147/cia.s120876 |
| Pubmed ID | |
| Authors |
Adriana de Oliveira Sarmento, Amilton da Cruz Santos, Ivani Credidio Trombetta, Marciano Moacir Dantas, Ana Cristina Oliveira Marques, Leone Severino do Nascimento, Bruno Teixeira Barbosa, Marcelo Rodrigues Dos Santos, Maria do Amparo Andrade, Anna Myrna Jaguaribe-Lima, Maria do Socorro Brasileiro-Santos |
| Abstract |
The objective of this study was to evaluate cardiac autonomic control and muscle vasodilation response during isometric exercise in sedentary and physically active older adults. Twenty healthy participants, 10 sedentary and 10 physically active older adults, were evaluated and paired by gender, age, and body mass index. Sympathetic and parasympathetic cardiac activity (spectral and symbolic heart rate analysis) and muscle blood flow (venous occlusion plethysmography) were measured for 10 minutes at rest (baseline) and during 3 minutes of isometric handgrip exercise at 30% of the maximum voluntary contraction (sympathetic excitatory maneuver). Variables were analyzed at baseline and during 3 minutes of isometric exercise. Cardiac autonomic parameters were analyzed by Wilcoxon and Mann-Whitney tests. Muscle vasodilatory response was analyzed by repeated-measures analysis of variance followed by Tukey's post hoc test. Sedentary older adults had higher cardiac sympathetic activity compared to physically active older adult subjects at baseline (63.13±3.31 vs 50.45±3.55 nu, P=0.02). The variance (heart rate variability index) was increased in active older adults (1,438.64±448.90 vs 1,402.92±385.14 ms, P=0.02), and cardiac sympathetic activity (symbolic analysis) was increased in sedentary older adults (5,660.91±1,626.72 vs 4,381.35±1,852.87, P=0.03) during isometric handgrip exercise. Sedentary older adults showed higher cardiac sympathetic activity (spectral analysis) (71.29±4.40 vs 58.30±3.50 nu, P=0.03) and lower parasympathetic modulation (28.79±4.37 vs 41.77±3.47 nu, P=0.03) compared to physically active older adult subjects during isometric handgrip exercise. Regarding muscle vasodilation response, there was an increase in the skeletal muscle blood flow in the second (4.1±0.5 vs 3.7±0.4 mL/min per 100 mL, P=0.01) and third minute (4.4±0.4 vs 3.9±0.3 mL/min per 100 mL, P=0.03) of handgrip exercise in active older adults. The results indicate that regular physical activity improves neurovascular control of muscle blood flow and cardiac autonomic response during isometric handgrip exercise in healthy older adult subjects. |
Mendeley readers
The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 86 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 14 | 16% |
| Student > Bachelor | 14 | 16% |
| Student > Ph. D. Student | 8 | 9% |
| Professor > Associate Professor | 5 | 6% |
| Student > Doctoral Student | 4 | 5% |
| Other | 13 | 15% |
| Unknown | 28 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Nursing and Health Professions | 14 | 16% |
| Sports and Recreations | 14 | 16% |
| Medicine and Dentistry | 11 | 13% |
| Neuroscience | 3 | 3% |
| Social Sciences | 3 | 3% |
| Other | 8 | 9% |
| Unknown | 33 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 February 2019.
All research outputs
#20,660,571
of 25,382,440 outputs
Outputs from Clinical Interventions in Aging
#1,550
of 1,968 outputs
Outputs of similar age
#254,491
of 330,503 outputs
Outputs of similar age from Clinical Interventions in Aging
#29
of 33 outputs
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