| Title |
New generation multi-modal antidepressants: focus on vortioxetine for major depressive disorder
|
|---|---|
| Published in |
Neuropsychiatric Disease and Treatment, February 2014
|
| DOI | 10.2147/ndt.s39544 |
| Pubmed ID | |
| Authors |
Cornelius L Katona, Cara P Katona |
| Abstract |
Vortioxetine is a novel antidepressant with effects on multiple 5-HT receptors and on the serotonin transporter. This paper reviews preclinical and clinical evidence regarding its mechanism of action, its tolerability, and its efficacy in treating major depression. Clinical studies indicate that vortioxetine is effective in the treatment of major depression, though there is no suggestion of superiority over active comparators. There may be a clinically meaningful advantage in terms of tolerability. |
X Demographics
The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 38% |
| South Africa | 1 | 13% |
| Unknown | 4 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 4 | 50% |
| Members of the public | 2 | 25% |
| Scientists | 2 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 109 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| New Zealand | 1 | <1% |
| Chile | 1 | <1% |
| Denmark | 1 | <1% |
| Germany | 1 | <1% |
| Unknown | 105 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 24 | 22% |
| Student > Master | 14 | 13% |
| Student > Bachelor | 11 | 10% |
| Student > Ph. D. Student | 10 | 9% |
| Other | 9 | 8% |
| Other | 27 | 25% |
| Unknown | 14 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 42 | 39% |
| Neuroscience | 12 | 11% |
| Agricultural and Biological Sciences | 9 | 8% |
| Biochemistry, Genetics and Molecular Biology | 6 | 6% |
| Psychology | 6 | 6% |
| Other | 13 | 12% |
| Unknown | 21 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 February 2018.
All research outputs
#7,118,925
of 25,584,565 outputs
Outputs from Neuropsychiatric Disease and Treatment
#882
of 3,120 outputs
Outputs of similar age
#77,653
of 323,682 outputs
Outputs of similar age from Neuropsychiatric Disease and Treatment
#13
of 58 outputs
Altmetric has tracked 25,584,565 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 3,120 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.6. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 323,682 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 75% of its contemporaries.
We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 79% of its contemporaries.