| Title |
Kidney function and cognitive decline in an oldest-old Chinese population
|
|---|---|
| Published in |
Clinical Interventions in Aging, July 2017
|
| DOI | 10.2147/cia.s134205 |
| Pubmed ID | |
| Authors |
Kunhao Bai, Yujing Pan, Fanghong Lu, Yingxin Zhao, Jinwei Wang, Luxia Zhang |
| Abstract |
Early-stage chronic kidney disease has been suggested to be correlated with cognitive decline, but the association has rarely been explored in the oldest old. This prospective study included 284 Chinese participants aged 80 years or older with serum creatinine levels <150 µmol/L. The median follow-up time was 3.3 years, and 247 (87.0%) participants provided valid data at their last visit. Kidney function was evaluated by measuring the estimated glomerular filtration rate (eGFR) at baseline, and cognitive function was evaluated using the Mini-Mental State Examination (MMSE) at both baseline and annual visits. A reliable decrease in the MMSE score over the follow-up period was observed based on a Reliable Change Index of 1.645 (equivalent to a 90% confidence interval [CI]), which was used to define cognitive decline. Poisson regression models were built to analyze the association between baseline kidney function and cognitive decline. A total of 18 (7.3%) cases of incident cognitive decline were observed during the follow-up period. After adjusting for potential confounders, the relative risk of developing cognitive decline was 4.03 (95% CI 1.09-13.81) among participants with an eGFR of 30-59 mL/min/1.73 m(2) compared to participants with an eGFR of ≥60 mL/min/1.73 m(2). Early-stage chronic kidney disease was correlated with cognitive decline in an oldest-old Chinese population. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Canada | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 36 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 8 | 22% |
| Student > Master | 4 | 11% |
| Researcher | 3 | 8% |
| Student > Ph. D. Student | 3 | 8% |
| Student > Postgraduate | 2 | 6% |
| Other | 4 | 11% |
| Unknown | 12 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 8 | 22% |
| Nursing and Health Professions | 3 | 8% |
| Psychology | 2 | 6% |
| Neuroscience | 2 | 6% |
| Agricultural and Biological Sciences | 1 | 3% |
| Other | 4 | 11% |
| Unknown | 16 | 44% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 December 2022.
All research outputs
#3,416,577
of 25,382,440 outputs
Outputs from Clinical Interventions in Aging
#370
of 1,968 outputs
Outputs of similar age
#59,596
of 326,871 outputs
Outputs of similar age from Clinical Interventions in Aging
#13
of 32 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,968 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.1. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 326,871 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.