Title |
Recent advances in the ARID family: focusing on roles in human cancer
|
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Published in |
OncoTargets and therapy, February 2014
|
DOI | 10.2147/ott.s57023 |
Pubmed ID | |
Authors |
Chen Lin, Wei Song, Xinyu Bi, Jianjun Zhao, Zhen Huang, Zhiyu Li, Jianguo Zhou, Jianqiang Cai, Hong Zhao |
Abstract |
The human AT-rich interaction domain (ARID) family contains seven subfamilies and 15 members characterized by having an ARID. Members of the ARID family have the ability to regulate transcription and are involved in cell differentiation and proliferation. Accumulating evidence suggests that ARID family members are involved in cancer-related signaling pathways, highly mutated or differentially expressed in tumor tissues, and act as predictive factors for cancer prognosis or therapeutic outcome. Here we review the molecular biology and clinical studies concerned with the role played by the ARID family in cancer. This may contribute to our understanding of the initiation and progression of cancer from a novel point of view, as well as providing potential targets for cancer therapy. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Turkey | 1 | 1% |
Unknown | 83 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 23 | 27% |
Student > Bachelor | 14 | 17% |
Student > Master | 11 | 13% |
Researcher | 10 | 12% |
Student > Doctoral Student | 5 | 6% |
Other | 6 | 7% |
Unknown | 15 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 31 | 37% |
Agricultural and Biological Sciences | 16 | 19% |
Medicine and Dentistry | 12 | 14% |
Immunology and Microbiology | 3 | 4% |
Nursing and Health Professions | 1 | 1% |
Other | 6 | 7% |
Unknown | 15 | 18% |